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Comparative multilocus VNTR and SNP analysis of Bacillus anthracis vaccine strains

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Abstract

Comparative VNTR and SNP genotype analysis of four Bacillus anthracis strains (three vaccine and one virulent) was carried out using modern molecular-genetic typing methods. It is established that these strains formed four SNP patterns completely corresponding to the VNTR profiles. It was demonstrated none of the strains tested, except vaccine B. anthracis STI-1, could belong by SNP profile to three global genetic lines of the anthrax agent extended in the world.

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Authors and Affiliations

  1. Irkutsk Antiplague Research Institute, Federal Service for Supervision of Consumer Rights Protection and Human Welfare, ul. Trilissera 78, Irkutsk, 664047, Russia

    M. V. Afanas’ev, E. V. Kravets, Z. F. Dugarzhapova, V. E. Takaishvili, V. S. Polovinkina & S. V. Balakhonov

Authors
  1. M. V. Afanas’ev
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  2. E. V. Kravets
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  3. Z. F. Dugarzhapova
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  4. V. E. Takaishvili
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  5. V. S. Polovinkina
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  6. S. V. Balakhonov
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Corresponding author

Correspondence to M. V. Afanas’ev.

Additional information

Original Russian Text © M.V. Afanas’ev, E.V. Kravets, Z.F. Dugarzhapova, V.E. Takaishvili, V.S. Polovinkina, S.V. Balakhonov, 2014, published in Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya, 2014, No. 2, pp. 37–41.

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Afanas’ev, M.V., Kravets, E.V., Dugarzhapova, Z.F. et al. Comparative multilocus VNTR and SNP analysis of Bacillus anthracis vaccine strains. Mol. Genet. Microbiol. Virol. 29, 86–92 (2014). https://doi.org/10.3103/S0891416814020025

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  • DOI: https://doi.org/10.3103/S0891416814020025

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