Abstract
The varicella-zoster virus (VZV) is widespread and causes two types of diseases: varicella, a primary infection, and herpes zoster, a reactivation of disease. VZV is a genetically stable virus, although its genome contains such elements of genome instability as direct and inverted repeats, and single nucleotide polymorphisms. The structure of the VZV genome, the strategy and methods of genotyping, as well as genetic classification problems are reviewed.
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Original Russian Text © V.V. Demkin, V.N. Loparev, 2010, published in Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya, 2010, No. 4, pp. 19–23.
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Demkin, V.V., Loparev, V.N. Genetic variability and genotyping of varicella-zoster viruses. Mol. Genet. Microbiol. Virol. 25, 158–162 (2010). https://doi.org/10.3103/S0891416810040038
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DOI: https://doi.org/10.3103/S0891416810040038