Abstract
Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.
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Original Russian Text © Sh.Yu. Khapchaev, S.S. Gutor, I.P. Kaminskii, E.E. Kremer, S.V. Krivoshchekov, I.V. Mil’to, A.G. Pershina, I.V. Petrova, I.V. Saltykova, N.S. Subbotina, K.V. Khvorilova, 2013, published in Vestnik Moskovskogo Universiteta. Biologiya, 2013, No. 4, pp. 14–17.
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Khapchaev, S.Y., Gutor, S.S., Kaminskii, I.P. et al. Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. Moscow Univ. Biol.Sci. Bull. 68, 174–177 (2013). https://doi.org/10.3103/S0096392514010040
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DOI: https://doi.org/10.3103/S0096392514010040