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+276G>T single nucleotide polymorphism in the adiponectine (APM1) gene in donors from the Kharkiv population

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Abstract

+276G > T polymorphism in the adiponectine gene (APM1) was studied in 103 samples obtained from donors in the Kharkiv population (men/women: 64/38; 70 Ukrainian, 33 Russian). The T- and G-allele frequencies did not significantly differ between either men and women or between Russians and Ukrainians and comprised p T = 0.55 and p G = 0.45 in the general group. The genotype distribution deviated from the Hardy-Weinberg equilibrium: the heterozygote frequency was 1.55 times higher compared to the selectively neutral value, while the TT- and GG-homozygote frequencies were 0.55 and 0.33 of the equilibrium value, respectively.

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Authors and Affiliations

  1. Danilevskii Institute of Problems of Endocrine Pathology, Ukrainian Academy of Sciences, Kharkiv, Russia

    L. A. Atramentova, V. V. Poltorak, T. V. Tyzhnenko & A. R. Pochernyaev

  2. Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Russia

    M. Yu. Gorshunskaya

Authors
  1. L. A. Atramentova
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  2. V. V. Poltorak
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  3. T. V. Tyzhnenko
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  4. M. Yu. Gorshunskaya
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  5. A. R. Pochernyaev
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Correspondence to L. A. Atramentova.

Additional information

Original Russian Text © L.A. Atramentova, V.V. Poltorak, T.V. Tyzhnenko, M.Yu. Gorshunskaya, A.R. Pochernyaev, 2010, published in Tsitologiya i Genetika, 2010, Vol. 44, No. 6, pp. 40–44.

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Atramentova, L.A., Poltorak, V.V., Tyzhnenko, T.V. et al. +276G>T single nucleotide polymorphism in the adiponectine (APM1) gene in donors from the Kharkiv population. Cytol. Genet. 44, 361–364 (2010). https://doi.org/10.3103/S009545271006006X

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  • DOI: https://doi.org/10.3103/S009545271006006X

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