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Analysis of genetic variability in American Pit Bull Terrier breed of dogs with a high inbreeding level using microsatellite markers

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Abstract

The level of DNA polymorphism in 10 microsatellite loci of 27 American Pit Bull Terrier dogs with high percentage of blood and inbreeding coefficients of up to 43.8% was studied. The observed heterozygosity was higher than expected for this inbreeding level. The presence of a selection mechanism that prevents gametes from fusing to form a homozygosity genotype is suggested.

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Correspondence to L. N. Shinkarenko.

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Original Russian Text © L.N. Shinkarenko, O.G. Guliakova, V.A. Malienko, S.D. Melnychuk, V.G. Spyrydonov, 2010, published in Tsitologiya i Genetika, 2010, Vol. 44, No. 4, pp. 16–22.

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Shinkarenko, L.N., Guliakova, O.G., Malienko, V.A. et al. Analysis of genetic variability in American Pit Bull Terrier breed of dogs with a high inbreeding level using microsatellite markers. Cytol. Genet. 44, 206–211 (2010). https://doi.org/10.3103/S0095452710040031

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  • DOI: https://doi.org/10.3103/S0095452710040031

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