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Biocatalytic Synthesis of Conducting Poly(3,4-Ethylenedioxythiophene) Using a Natural DNA Template

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Abstract

The oxidative enzymatic polymerization of 3,4-ethylenedioxythiophene on a biopolymer DNA template is carried out. Laccase from fungus Trametes hirsuta with a high redox potential serves as a catalyst for the monomer polymerization; atmospheric oxygen is used as the oxidizing agent. Phosphate groups of DNA biopolymer, being dopants of the main chain of synthesized poly(3,4-ethylenedioxythiophene) (PEDOT), ensure its electrical conductivity. The physicochemical properties of the obtained complex and its morphology are studied. The conductivity of the PEDOT/DNA is ~0.15 mS/cm. The synthesized electrically conducting biocompatible PEDOT/DNA interpolymer complex can potentially be used for various biomedical purposes.

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Funding

This work was supported by the Russian Foundation for Basic Research, project no. 17-04-00378a.

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Authors and Affiliations

  1. Bach Institute of Biochemistry, Research Centre of Biotechnology, Russian Academy of Sciences, 119071, Moscow, Russia

    I. S. Vasil’eva, M. E. Khlupova, G. P. Shumakovich, O. V. Morozova & A. I. Yaropolov

  2. Department of Chemistry, Moscow State University, 119991, Moscow, Russia

    E. A. Zaitseva

Authors
  1. I. S. Vasil’eva
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  2. M. E. Khlupova
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  3. G. P. Shumakovich
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  4. E. A. Zaitseva
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  5. O. V. Morozova
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  6. A. I. Yaropolov
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Corresponding author

Correspondence to A. I. Yaropolov.

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The authors declare that they have no conflict of interest.

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Translated by O. Zhukova

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Vasil’eva, I.S., Khlupova, M.E., Shumakovich, G.P. et al. Biocatalytic Synthesis of Conducting Poly(3,4-Ethylenedioxythiophene) Using a Natural DNA Template. Moscow Univ. Chem. Bull. 74, 186–190 (2019). https://doi.org/10.3103/S0027131419040096

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  • DOI: https://doi.org/10.3103/S0027131419040096

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