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Cryochemical synthesis and antibacterial activity of a hybrid composition based on Ag nanoparticles and dioxidine

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Abstract

Hybrid nanocomposites based on an dioxidine antimicrobial substance modified with silver were produced by means of cryochemical synthesis. TEM, UV-absorption spectroscopy, X-ray diffraction, and surface analysis based on low-temperature argon adsorption showed the formation of hybrid nanosystems consisting of drug substance particles with a size of 50–300 nm including internal small Ag nanoparticles with a size of 2–40 nm. The obtained hybrid nanosystems showed higher antibacterial activity against E. coli 52, S. aureus 144, and M. cyaneum 98 than did the original dioxidine.

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Authors and Affiliations

  1. Department of Chemistry, Moscow State University, Moscow, 119991, Russia

    O. I. Vernaya, V. P. Shabatin, A. M. Semenov & T. I. Shabatina

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  1. O. I. Vernaya
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  2. V. P. Shabatin
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  3. A. M. Semenov
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  4. T. I. Shabatina
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Corresponding author

Correspondence to O. I. Vernaya.

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Original Russian Text © O.I. Vernaya, V.P. Shabatin, A.M. Semenov, T.I. Shabatina, 2016, published in Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya, 2016, No. 6, pp. 388–391.

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Vernaya, O.I., Shabatin, V.P., Semenov, A.M. et al. Cryochemical synthesis and antibacterial activity of a hybrid composition based on Ag nanoparticles and dioxidine. Moscow Univ. Chem. Bull. 72, 6–9 (2017). https://doi.org/10.3103/S002713141701014X

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  • DOI: https://doi.org/10.3103/S002713141701014X

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