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Synthesis and bioassay of benzimidazole conjugates with adamantane

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Moscow University Chemistry Bulletin Aims and scope

Abstract

The synthesis of 2-adamantyl-6-[(1H-benzimidazol-1-ylcarbonyl)amino]hexanoate and 2-adamantyl-7-(1H-benzimidazol-1-yl)-7-oxo-heptanoate, and the results of their cytotoxicity assay against human lung carcinoma cells A549 are presented in the paper. The impossibility of adding 5-(2-adamantyloxycarbonyl)pentyl isocyanate to nocodazole under various conditions was shown.

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Authors and Affiliations

  1. Moscow State University, Moscow, Russia

    E. V. Nurieva, A. A. Beloglazkyna, D. V. Shishov, V. V. Gogol, Ya. S. Glazkova, N. S. Zefirov & O. N. Zefirova

  2. Institute of Biological Sciences, Cell Biology and Biosystems Technology, University of Rostock, Rostock, Germany

    B. Wobith & S. A. Kuznetsov

  3. Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka, Moscow oblast, Russia

    N. S. Zefirov & O. N. Zefirova

Authors
  1. E. V. Nurieva
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  2. A. A. Beloglazkyna
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  3. D. V. Shishov
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  4. V. V. Gogol
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  5. Ya. S. Glazkova
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  6. B. Wobith
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  7. N. S. Zefirov
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  8. S. A. Kuznetsov
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  9. O. N. Zefirova
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Corresponding author

Correspondence to Ya. S. Glazkova.

Additional information

Original Russian Text © E.V. Nurieva, A.A. Beloglazkyna, D.V. Shishov, V.V. Gogol, Ya.S. Glazkova, B. Wobith, N.S. Zefirov, S.A. Kuznetsov, O.N. Zefirova, 2013, published in Vestnik Moskovskogo Universiteta. Khimiya, 2013, No. 1, pp. 45–48.

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Nurieva, E.V., Beloglazkyna, A.A., Shishov, D.V. et al. Synthesis and bioassay of benzimidazole conjugates with adamantane. Moscow Univ. Chem. Bull. 68, 37–40 (2013). https://doi.org/10.3103/S0027131413010094

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  • DOI: https://doi.org/10.3103/S0027131413010094

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