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Information system for antitumor agents: Computer database registration and nomenclature module

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Automatic Documentation and Mathematical Linguistics Aims and scope

Abstract

A general description of the corporate information system for antitumor agents of the Blokhin Cancer Research Center (CRC), a complex representing an archive of primary documents, paper cards with formalized information, and a computer database in ISIS/Base format, is given. The system contains data on the chemical structure, composition, physicochemical properties, and biological activity of 11 000 entities investigated at the CRC and is used for the information support of work on the search for new antitumor preparations.

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References

  1. Larionov, L.F. and Mankin, Z.V., Biological and Chemical Methods of Cancer Treatment, Malignant Tumors, vol. 1, pt. 2, Petrov, N.N., Ed., Leningrad, Medgiz, 1948, pp. 117–152.

    Google Scholar 

  2. Larionov, L.F., Malignant Tumors Therapy, Moscow: Meditsina, 1962.

    Google Scholar 

  3. The System of Creation of Antitumor Preparations in the USSR and USA, Blokhin, N.N. and Zubroda, Ch.G., Eds., Moscow: Meditsina, 1977.

    Google Scholar 

  4. Experimental Assessment of Antitumor Preparations in the USSR and USA, Sof’in, Z.P., Syrkin, A.B., Goldin, A., and Klain, A., Eds., Moscow: Meditsina, 1980.

    Google Scholar 

  5. Gerasimova, G.K. and Apryshko, G.N., Development of the Selection Systems and Methods for Substances with Antitumor Properties at the N.N. Blokhin RORC, RAMS, in Experimental Oncology between the Centuries, Davydov, M.I., Baryshnikov, A.K., Eds., Press Group of the N.N. Blokhin RORC, RAMS, 2003, pp. 59–84.

  6. Procedure for Organizing Work on the Development of Antitumor Drugs and Their Preparation for Clinical Trials at the All-Union Cancer Research Center of the USSR Academy of Medical Sciences and on Participation in Their Introduction to Industrial Production, USSR AMS All-Union Oncology Center, 1984.

  7. Apryshko, G.N., The Databank Monitoring System Tumor Chemotherapy of Research Institute of Experimental Diagnostics and Tumors Treatment and AMS All-Union Oncology Center, Chemotherapy of Tumors in the USSR, 1987, issue 47, pp. 217–232.

  8. Apryshko, G.N., Syutkina, N.I., and Kupchan, D.Z., The Rater Card Index Monitoring — Clinic, of the New Drugs Study Coordination Group, Chemotherapy of Tumors in the USSR, 1988, issue 51, pp. 164–167.

  9. Apryshko, G.N., Bystrov, L.V., Gerasimova G.M., Parfent’ev, S.V., Suchkov, A.P., and Yanik, A.A., Databank on Antitumor Preparations, Abstracts of IX All-Union Conference Chemical Informatics, Chernogolovka, 1992, p. 55.

  10. Apryshko, G.N., Application-Oriented Databank on Antitumor Preparations, Abstracts of II Russian National Congress Man and Drug, Moscow, 1995, p. 63.

  11. Apryshko, G.N., Russian Research Oncology Center Databank on Antitumor Agents, Materials of V All-Russian Congress of Oncologists High Technologies in Oncology, Kazan, October 4–7, 2000, vol. 1, pp. 131–133.

  12. Apryshko, G.N., Information System for Antitumor Agents, Ross. Bioterapevticheskii Zh., 2002, no. 2, Materials of I All-Russian Scientific and Practical Conference with foreign participants Otechestvennyye Protivoopukholevyye Preparaty (Home Antineoplastic Preparations), Moscow, March 17–20, 2002, pp. 7–10.

  13. http://www.mdl.com.

  14. Apryshko, G.N. and Reshetnikova, V.V., The Linguistic Support of the RAMS CRC Electronic Database on Antitumor Preparations, The original was deposited with the RAS VINITI on July 19, 2006, no. 976-V2006.

  15. Apryshko, G.N., Poroikov, V.V., and Filimonov, D.A., Computer Prediction of the Antineoplastic Activity Spectrum, Abstracts of XII Russian National Congress Man and Drug, Moscow, April 18–22, 2005, p. 636.

  16. Kumskov, M.I., Apryshko, G.N., Gerasimova, G.K., Maslova, L.K., Prediction of Cytological Activity of the Fluoro-Containing Organic Compounds Using a Microcomputer, Abstracts of 1st Int. Conf. Chemistry, Technology and Industrial Application of Fluoro-Containing Compounds, St.-Petersburg, 1994, p. 116.

  17. Apryshko, G.N., Reshetnikova, V.V., Gerasimova, G.K., Kumskov, M.I., Maslova, L.K., and Zefirov, N.S., The Prediction of the Cytotoxical Activity of Chemicals with the Computerized BIBIGON System, Abstracts of 5th Int. Symp. on Molecular Aspects of Chemotherapy, Gdansk, Poland, August 21–24, 1995, p. 47.

  18. Apryshko, G.N., Kumskov, M.I., Reshetnikova, V.V., Maslova, L.K., and Ponomareva L.A., The Database on Antitumor Preparations for Studying the STRUCTURE-ACTIVITY Correlation, Materials of 6th Int. Conference Images Recognition and Analysis: New Information Technologies, ROAI-6-2002, Velikii Novgorod, RF, October 21–26, 2002, pp. 39–40.

  19. Samokhin, M.V., Apryshko, G.N., Goryunova, O.V., Plikhtyak, I.L., and Reshetnikova, V.V., Prediction of the Biological Activity in Glycosides of Bisyndols and Indolocarbasols, Based on the Representation of Molecules by Marked Graphs with Taking into Account the Stereoisomerism, Abstracts of XIII Russian National Congress Man and Drug, Moscow, 2006, p. 35.

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Authors
  1. G. N. Apryshko
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Original Russian Text © G.N. Apryshko, 2007, published in Nauchno-Tekhnicheskaya Informatsiya, Seriya 2, 2007, No. 1, pp. 18–22.

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Apryshko, G.N. Information system for antitumor agents: Computer database registration and nomenclature module. Autom. Doc. Math. Linguist. 41, 6–10 (2007). https://doi.org/10.3103/S0005105507010025

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  • DOI: https://doi.org/10.3103/S0005105507010025

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