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Bulletin of the Lebedev Physics Institute

, Volume 46, Issue 10, pp 306–308 | Cite as

Physical Interactions of Biopolymers with Nanoparticles

  • A. V. KosmyntsevaEmail author
  • I. O. Petrova
  • Yu. P. Rakovich
  • A. V. Sukhanova
  • I. R. Nabiev
Article
  • 7 Downloads

Abstract

Using fluorescence resonance energy transfer, the physical interaction of nanoparticles with biopolymers is studied by the example of the interaction of quantum dots (energy donor) with two-chain oligonucleotides labeled with a fluorescent organic dye BDP TR (energy acceptor). The high-efficiency resonance energy transfer from quantum dots to an organic dye not only makes it possible to study the dependence of the transfer efficiency on the donor-acceptor molar ratio but also represents an efficient tool for studying the interactions of oligonucleotides of different structures with nanoscale objects.

Keywords

quantum dots oligonucleotides fluorescence resonance energy transfer FRET 

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Notes

Acknowledgments

This study was supported by the Ministry of Higher Education and Science of the Russian Federation, project no. 14.Y26.31.0011.

References

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Copyright information

© Allerton Press, Inc. 2019

Authors and Affiliations

  • A. V. Kosmyntseva
    • 1
    Email author
  • I. O. Petrova
    • 1
  • Yu. P. Rakovich
    • 1
    • 2
    • 3
  • A. V. Sukhanova
    • 4
  • I. R. Nabiev
    • 1
    • 4
  1. 1.National Research Nuclear University “MEPhI”MoscowRussia
  2. 2.Center for Materials Physics and University of the Basque CountryDonostia—San SebastiánSpain
  3. 3.IKERBASQUE, Basque Foundation for ScienceBilbaoSpain
  4. 4.Laboratoire de Recherche en Nanosciences, EA4682-LRNUniversité de Reims Champagne-ArdenneReimsFrance

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