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Cytology and Genetics

, Volume 50, Issue 1, pp 32–41 | Cite as

Immunohistochemical and biochemical analysis of mammary gland tumours of different age patients

  • T. LykholatEmail author
  • O. Lykholat
  • S. Antonyuk
Article

Abstract

Immunohistochemical and biochemical study of infiltrative ductal breast carcinoma and tissue adjacent to the tumour revealed a particular molecular profile and characteristics of the oxidant-antioxidant status neoplasms depending on the age of the patients and the presence of metastases in regional lymph nodes. Some causes of high aggressiveness and low hormone sensitivity of tumours in premenopausal women, as well as stability and high metastatic potential of tumours in postmenopausal women have been found.

Keywords

breast tumours the molecular profile oxidant-antioxidant characteristics metastasis menopausal status 

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Copyright information

© Allerton Press, Inc. 2016

Authors and Affiliations

  1. 1.Oles Honchar Dnipropetrovsk National UniversityDnipropetrovskUkraine
  2. 2.University Customs Business and FinanceDnipropetrovskUkraine
  3. 3.Regional Cancer CentreDnipropetrovskUkraine

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