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Comparison of clavicular joints in human and laboratory rat

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Abstract

The human clavicle provides the bony connection between the upper extremity and the axial skeleton and it is reported to be among the first bones ossified and the last bone to fuse. Clavicle development of the studied mammals shows a combination of intramembranous and endochondrial ossification. The covering of its joints in adult humans differs from other joints of long bones. The rat clavicle pattern morphologically appears to be partly different in comparison with the human one. These differences partially restrict the use of the rat as a model for the study of human articular cartilage but on the other hand they can provide some valuable possibilities for application in medical research and practice.

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Abbreviations

ACJ:

acromioclavicular joint

BM:

bone marrow

CF:

collagenic fibers

Ch:

chondrocytic cell layer

F:

fibrous layer

H:

hypertrophic cell layer

HE:

hematoxylin and eosin

M:

mitotic figs

O:

ossification zones

P:

proliferative cell layer

SCJ:

sternoclavicular joint

TMJ:

temporomandibular joint

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Acknowledgments

The authors thank Mrs. Lubica Bošmanska and Alexandra Machova for assistance during the preparation of histological specimens. This work was partly supported by the APVV-15-0372 and by theVEGA-2/0129/15 grants.

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Authors and Affiliations

  1. Institute of Histology and Embryology, Faculty of Medicine, Comenius University in Bratislava, Sasinkova 4, Bratislava, 811 08, Slovak Republic

    Ján Líška & Štefan Polák

  2. Department of Orthopedics, Faculty of Medicine, Comenius University in Bratislava, Špitálska 24, Bratislava, 813 72, Slovak Republic

    Radoslav Zamborský

  3. Department of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy, Komenského 73, Košice, 041 81, Slovak Republic

    Dávid Maženský

  4. Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 841 04, Slovak Republic

    Eduard Ujházy

  5. Institute of Anatomy, Faculty of Medicine, Comenius University in Bratislava, Sasinkova 2, Bratislava, 811 08, Slovak Republic

    Peter Malovec

  6. Institute of Experimental Endocrinology, Biomedical Researche Centre, Dúbravská cesta 9, Slovak Academy of Sciences, Vlárska 3, Bratislava, 833 06, Slovak Republic

    Július Brtko

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  1. Ján Líška
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  2. Radoslav Zamborský
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Correspondence to Ján Líška.

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The bone sample of human clavicle originates from donor cadaver for science purposes at the Institute of Anatomy of Medical Faculty of Comenius University Bratislava, Slovak Republic and it was provided by a staff member of mentioned institution - co-author of this publication.

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Líška, J., Zamborský, R., Maženský, D. et al. Comparison of clavicular joints in human and laboratory rat. Biologia 73, 1247–1254 (2018). https://doi.org/10.2478/s11756-018-0130-6

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