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Environmentally benign one-pot synthesis and antimicrobial activity of 1-methyl-2,6-diarylpiperidin-4-ones

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Abstract

An efficient and environmentally benign one-pot method for the synthesis of 1-methyl-2,6-diarylpiperidin-4-ones using montmorillonite K-10 as a catalyst has been developed. Antimicrobial activity of the compounds has been tested against selected representatives of Gram-positive and Gram-negative bacteria and fungi.

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Authors and Affiliations

  1. Organic Chemistry Division, School of Advanced Sciences, Vellore, Tamil Nadu, 632 014, India

    Pattusamy Nithya, Fazlur-Rahman Nawaz Khan & Selvaraj Mohana Roopan

  2. School of Bio Sciences & Technology, VIT University, Vellore, Tamil Nadu, 632 014, India

    Uma Shankar

  3. Division of High Technology Materials Research, Busan Center, Korea Basic Science Institute (KBSI), Busan, 618-230, Republic of Korea

    Fazlur-Rahman Nawaz Khan & Jong Sung Jin

Authors
  1. Pattusamy Nithya
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  2. Fazlur-Rahman Nawaz Khan
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  3. Selvaraj Mohana Roopan
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  4. Uma Shankar
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  5. Jong Sung Jin
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Nithya, P., Nawaz Khan, FR., Roopan, S.M. et al. Environmentally benign one-pot synthesis and antimicrobial activity of 1-methyl-2,6-diarylpiperidin-4-ones. Chem. Pap. 65, 743–746 (2011). https://doi.org/10.2478/s11696-011-0046-x

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  • DOI: https://doi.org/10.2478/s11696-011-0046-x

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