Abstract
For the first time, synthesis of AB ring core of camptothecin synthons such as (2-chloroquinolin-3-yl)methanols (Va-Vg) using zinc oxide nanoparticles is reported. The desired attractive products were obtained in high yields, short reaction time, using a simple work-up procedure with the purification of products by non-chromatographic methods.
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Roopan, S.M., Nawaz Khan, F.R. ZnO nanoparticles in the synthesis of AB ring core of camptothecin. Chem. Pap. 64, 812–817 (2010). https://doi.org/10.2478/s11696-010-0058-y
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DOI: https://doi.org/10.2478/s11696-010-0058-y