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ZnO nanorods catalyzed N-alkylation of piperidin-4-one, 4(3H)-pyrimidone, and ethyl 6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline-3-carboxylate

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Abstract

An efficient ligand-free cross-coupling reaction of 2-chloro-3-(chloromethyl)benzo[h]quinoline with N-heterocycles such as piperidin-4-one, 4(3H)-pyrimidone, and ethyl 6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline-3-carboxylate using a catalytic amount of ZnO nanorods as a recyclable catalyst and KOH as the base in DMSO under reflux at 110°C is reported.

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Authors and Affiliations

  1. Organic and Medicinal Chemistry Research Laboratory, Organic Chemistry Division, School of Advanced Sciences, VIT University, Vellore, India

    Selvaraj Mohana Roopan & Fazlur Rahman Nawaz Khan

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  1. Selvaraj Mohana Roopan
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  2. Fazlur Rahman Nawaz Khan
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Correspondence to Fazlur Rahman Nawaz Khan.

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Roopan, S.M., Khan, F.R.N. ZnO nanorods catalyzed N-alkylation of piperidin-4-one, 4(3H)-pyrimidone, and ethyl 6-chloro-1,2-dihydro-2-oxo-4-phenylquinoline-3-carboxylate. Chem. Pap. 64, 678–682 (2010). https://doi.org/10.2478/s11696-010-0045-3

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  • DOI: https://doi.org/10.2478/s11696-010-0045-3

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