Acta Parasitologica

, Volume 64, Issue 3, pp 514–519 | Cite as

Epidemiological Investigation of Toxoplasma gondii Infections in Commercial Sheep Flock in an Endemic Area for Ocular Toxoplasmosis in Southern Brazil

  • Angélica ConsalterEmail author
  • Edwards Frazão-Teixeira
  • Jitender P. Dubey
  • Eraldo L. Zanella
  • Andressa F. da Silva
  • Guilherme N. de Souza
  • Ana M. R. Ferreira
Short Communication



Toxoplasma gondii is a widely distributed parasite and of great importance to human and animal health.


The objective of this study was to assess the prevalence of T. gondii antibodies and risk factors associated with the infection in sheep in the Northwest region of the State of Rio Grande do Sul, Brazil; this region has a very high rate of human ocular toxoplasmosis. Ovine sera were tested by the modified agglutination test (cut-off 1:25).


T. gondii antibodies were detected in 70.2% (224 of 319). According to the logistic regression, the most significant factors associated were age and cat access to food stock facility.


Preventive measures are discussed to reduce the risk of transmission of this zoonosis.


Toxoplasmosis Sheep Risk factors MAT 



The authors would like to give special thanks to the all farmers and to Rogério Nadal, Veterinarian of Universidade de Passo Fundo, for their collaboration in this study. This work was supported by FAPERJ and CNPq.


  1. 1.
    Almería S, Cabezón O, Paniagua J, Cano-Terriza D, Jiménez-Ruiz S, Arenas Montes A, Dubey JP, García-Bocanegra I (2018) Toxoplasma gondii in sympatric domestic and wild ungulates in the Mediterranean ecosystem. Parasitol Res 117:665–671. CrossRefPubMedGoogle Scholar
  2. 2.
    Andrade MMC, Carneiro M, Medeiros AD, Neto VA, Vitor RWA (2013) Seroprevalence and risk factors associated with ovine toxoplasmosis in Northeast Brazil. Parasite. CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Arantes TEF, Silveira C, Holland GN, Muccioli C, Yu F, Jones JL, Goldhardt R, Lewis KG, Belfort R (2015) Ocular involvement following postnatally acquired Toxoplasma gondii infection in Southern Brazil: a 28-year experience. Am J Ophthalmol 159:1002–1012.e2. CrossRefPubMedGoogle Scholar
  4. 4.
    Boughattas S, Ayari K, Sa T, Aoun K, Bouratbine A (2014) Survey of the parasite Toxoplasma gondii in human consumed ovine meat in Tunis City. PLoS One 9:e85044. CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    CDC (2002) EpiInfo 7.1.5. Centers for Disease Control and Prevention. EpiInfo 7.1.5. Accessed 12 June 2016
  6. 6.
    Correia ÉLB, Feitosa TF, dos Santos FA, de Azevedo SS, Pena HFJ, Gennari SM, Mota RA, Alves CJ (2015) Prevalence and risk factors for Toxoplasma gondii in sheep in the State of Paraíba, Northeastern Brazil. Revista Brasileira de Parasitologia Veterinária 24:383–386. CrossRefPubMedGoogle Scholar
  7. 7.
    Cosendey-Kezen Leite RIJ, de Oliveira FCR, Frazão-Teixeira E, Dubey JP, de Souza GN, Ferreira AMR, Lilenbaum W (2014) Occurrence and risk factors associated to Toxoplasma gondii infection in sheep from Rio de Janeiro, Brazil. Trop Anim Health Prod 46:1463–1466. CrossRefGoogle Scholar
  8. 8.
    Dubey JP (2010) Toxoplasmosis of animals and humans second edition, 2nd edn. CRC Press, Boca RatonGoogle Scholar
  9. 9.
    Dubey JP, Desmonts G (1987) Serological responses of equids fed Toxoplasma gondii oocysts. Equine Vet J 19:337–339CrossRefGoogle Scholar
  10. 10.
    Dubey JP, Sundar N, Hill D, Velmurugan GV, Bandini LA, Kwok OCH, Majumdar D, Su C (2008) High prevalence and abundant atypical genotypes of Toxoplasma gondii isolated from lambs destined for human consumption in the USA. Int J Parasitol 38:999–1006. CrossRefPubMedGoogle Scholar
  11. 11.
    Dubey JP, Lago EG, Gennari SM, Su C, Jones JL (2012) Toxoplasmosis in humans and animals in Brazil: high prevalence, high burden of disease, and epidemiology. Parasitology 139:1375–1424. CrossRefPubMedGoogle Scholar
  12. 12.
    Edwards JF, Dubey JP (2013) Toxoplasma gondii abortion storm in sheep on a Texas farm and isolation of mouse virulent atypical genotype T. gondii from an aborted lamb from a chronically infected ewe. Vet Parasitol 192:129–136. CrossRefPubMedGoogle Scholar
  13. 13.
    Glasner PD, Silveira C, Kruszon-Moran D, Martins MC, Burnier M, Silveira S, Camargo ME, Nussenblatt RB, Kaslow RA, Belfort R (1992) An unusually high prevalence of ocular toxoplasmosis in Southern Brazil. Am J Ophthalmol 114:136–144. CrossRefPubMedGoogle Scholar
  14. 14.
    Guimarães LA, Bezerra RA, Rocha DS, Albuquerque GR (2013) Prevalence and risk factors associated with anti-Toxoplasma gondii antibodies in sheep from Bahia state, Brazil. Revista Brasileira de Parasitologia Veterinária 22:220–224. CrossRefPubMedGoogle Scholar
  15. 15.
    Halos L, Thébault A, Aubert D, Thomas M, Perret C, Geers R, Alliot A, Escotte-Binet S, Ajzenberg D, Dardé M-L, Durand B, Boireau P, Villena I (2010) An innovative survey underlining the significant level of contamination by Toxoplasma gondii of ovine meat consumed in France. Int J Parasitol 40:193–200. CrossRefPubMedGoogle Scholar
  16. 16.
    Hecker YP, Masson FM, Armendano JI, Cora J, Olivares CF, Gual I, Pardini L, Moore DP, Moré G, Cantón GJ (2018) Evaluation of frequency of antibodies against Toxoplasma gondii, Neospora caninum and Sarcocystis spp. and transmission routes in sheep from Humid Pampa, Argentina. Acta Parasitol 63:416–421. CrossRefPubMedGoogle Scholar
  17. 17.
    Holland GN (2003) Ocular toxoplasmosis: a global reassessment: part I: epidemiology and course of disease. Am J Ophthalmol 136:973–988. CrossRefPubMedPubMedCentralGoogle Scholar
  18. 18.
    IBGE (2014) Instituto Brasileiro de Geografia e Estatística, n.d. Efetivo do rebanho de ovinos em 2014. Accessed 12 June 2016Google Scholar
  19. 19.
    Liu Z-K, Li J-Y, Pan H (2015) Seroprevalence and risk factors of Toxoplasma gondii and Neospora caninum infections in small ruminants in China. Prev Vet Med 118:488–492. CrossRefPubMedGoogle Scholar
  20. 20.
    Lúcio ÉC, Pimentel JDL, Clemente SMDS, Sá LMN, Oliveira JMB, Albuquerque PPF, Mota RA, Pinheiro Junior JW (2017) Epidemiological analysis of Toxoplasma gondii infection in sheep in the state of Pernambuco, Brazil. Semina: Ciências Agrárias. 38:3059. CrossRefGoogle Scholar
  21. 21.
    Magalhães FJR, Ribeiro-Andrade M, de Alcântara AM, Pinheiro Júnior JW, de Sena MJ, Porto WJN, Vieira RFC, Mota RA (2016) Risk factors for Toxoplasma gondii infection in sheep and cattle from Fernando de Noronha Island, Brazil. Revista Brasileira de Parasitologia Veterinária 25:511–515. CrossRefPubMedGoogle Scholar
  22. 22.
    Mendonça CED, Barros SLB, Guimarães VAA, Ferraudo AS, Munhoz AD (2013) Prevalence and risk factors associated to ovine toxoplasmosis in northeastern Brazil. Revista Brasileira de Parasitologia Veterinária 22:230–234. CrossRefPubMedGoogle Scholar
  23. 23.
    Nunes ACBT, da Silva EMV, de Oliveira JA, Yamasaki EM, Kim PCP, de Almeida JC, Nunes KB, Mota RA (2015) Application of different techniques to detect Toxoplasma gondii in slaughtered sheep for human consumption. Revista Brasileira de Parasitologia Veterinária 24:416–421. CrossRefPubMedGoogle Scholar
  24. 24.
    De Oliveira FC, de Oliveira PA, Da Cunha Filho NA, Aguiar CLG, Pappen FG, Ruas JL, Da Rosa Farias NA (2016) The incidence and productive significance of ovine toxoplasmosis in Southern Brazil. Cienc Rural 46:1618–1621. CrossRefGoogle Scholar
  25. 25.
    Rêgo WMF, Paula NRO, Vitor RWA, Silva RAB, Diniz BLM, Sousa MM, Coelho WAC, Porfirio KP, Pinheiro RR, Alves FSF, Cavalcante ACR, Cardoso JFS (2016) Risk factors for Toxoplasma gondii infection in goats and sheep raised in the State of Piauí in northeast Brazil. Small Rumin Res 141:17–23. CrossRefGoogle Scholar
  26. 26.
    Tilahun B, Tolossa YH, Tilahun G, Ashenafi H, Shimelis S (2018) Seroprevalence and risk factors of Toxoplasma gondii Infection among domestic ruminants in east Hararghe Zone of Oromia Region, Ethiopia. Vet Med Int 20:25. CrossRefGoogle Scholar

Copyright information

© Witold Stefański Institute of Parasitology, Polish Academy of Sciences 2019

Authors and Affiliations

  • Angélica Consalter
    • 1
    Email author
  • Edwards Frazão-Teixeira
    • 2
  • Jitender P. Dubey
    • 3
  • Eraldo L. Zanella
    • 4
  • Andressa F. da Silva
    • 5
  • Guilherme N. de Souza
    • 6
  • Ana M. R. Ferreira
    • 1
    • 7
  1. 1.Programa de Pós-Graduação em Medicina Veterinária (Clínica e Reprodução Animal)Universidade Federal FluminenseNiteróiBrazil
  2. 2.Laboratório de Biologia EstruturalInstituto Oswaldo Cruz, IOC/FiocruzRio de JaneiroBrazil
  3. 3.Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research CenterAgricultural Research Service, United States Department of AgricultureBeltsvilleUSA
  4. 4.Laboratório de Reprodução e Melhoramento Genético AnimalUniversidade de Passo FundoPasso FundoBrazil
  5. 5.Departamento de Medicina e Cirurgia VeterinariaUniversidade Federal Rural do Rio de JaneiroSeropédicaBrazil
  6. 6.Embrapa Gado de LeiteJuiz de ForaBrazil
  7. 7.Departamento de Patologia e Clínica VeterináriaUniversidade Federal FluminenseNiteróiBrazil

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