Central European Journal of Medicine

, Volume 9, Issue 3, pp 382–390 | Cite as

The role of genetic and other biomarkers in NSCLC prognosis

  • Diana SchveigertEmail author
  • Saulius Cicenas
  • Jaroslav Bublevic
  • Renatas Askinis
  • Virginijus Sapoka
  • Janina Didziapetriene


The development of non-small-cell lung cancer (NSCLC) is a multistep process, which is triggered and maintained by various factors. Many steps of non-small-cell lung carcinogenesis, risk factors and biomarkers have been identified; however no consistent model has been established of personalized medicine for these patients. Distinct various gene expression, products of mutated genes and other markers such as circulating nucleic acids or tumor cells has been proven to be potential biomarkers of non-small cell lung cancer as well as potential targets for new treatment strategies. This article will highlight promising biomarkers in non-small cell lung cancer prognosis.


Non-small cell lung cancer Biomarkers Prognosis 


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Copyright information

© Versita Warsaw and Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Diana Schveigert
    • 1
    Email author
  • Saulius Cicenas
    • 1
    • 2
  • Jaroslav Bublevic
    • 2
  • Renatas Askinis
    • 1
    • 2
  • Virginijus Sapoka
    • 1
    • 2
  • Janina Didziapetriene
    • 1
    • 2
  1. 1.Institute of OncologyVilnius UniversityVilniusLithuania
  2. 2.Faculty of MedicineVilnius UniversityVilniusLithuania

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