Central European Journal of Medicine

, Volume 9, Issue 1, pp 40–44 | Cite as

Increased aortic stiffness in ulcerative colitis

  • Attila Nemes
  • Henriette Gavallér
  • Ferenc Nagy
  • József Náfrády
  • Tibor Wittmann
  • Tamás Forster
Research Article



Ulcerative colitis (UC) is a chronic inflammatory disease of the colon. Currently, there is an increased scientific interest in the evaluation of early functional vascular alterations, especially in inflammatory disorders. The present study was aimed to examine whether UC is associated with abnormalities in aortic elasticity.


The study was comprised of 11 UC patients (mean age 39 ± 12 years, 7 males), their results were compared to 22 age- and gender-matched controls. All subjects underwent a complete two-dimensional transthoracic Doppler echocardiography including evaluation of aortic elastic properties. The oscillometry-based Arteriograph device was used in all cases to measure aortic pulse-wave velocity (PWV) and augmentation index (Aix).


Despite similar blood pressure values, aortic stiffness index, PWV and Aix were significantly increased, while pulsatile change in aortic diameter, aortic strain and aortic distensibility were significantly decreased in UC patients compared to controls.


Abnormal echocardiographic aortic elastic properties and Arteriograph-derived pulse-wave velocity could be demonstrated in patients with ulcerative colitis.


Aortic Stiffness Distensibility Ulcerative colitis 


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Copyright information

© Versita Warsaw and Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Attila Nemes
    • 1
  • Henriette Gavallér
    • 1
  • Ferenc Nagy
    • 2
  • József Náfrády
    • 2
  • Tibor Wittmann
    • 2
  • Tamás Forster
    • 1
  1. 1.2nd Department of Medicine and Cardiology Centre, Medical Faculty, Albert Szent-Györgyi Clinical CentreUniversity of SzegedSzegedHungary
  2. 2.1st Department of Medicine, Medical Faculty, Albert Szent-Györgyi Clinical CentreUniversity of SzegedSzegedHungary

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