Central European Journal of Medicine

, Volume 8, Issue 6, pp 871–878 | Cite as

Independent and combined interaction of fine particulate matter in atmospheric air and the frequency of acute myocardial infarction hospitalizations in Varna, Bulgaria

  • Emiliya Karaslavova
  • Teodora Dimitrova
  • Nikolai Donchev
  • Bilyana Teneva
  • Pavel Timonov
Research Article



To explore the relationship between atmospheric particulate matter concentrations and the frequency of acute myocardial infarction (AMI) hospitalizations.

Materials and methods

The relationship between air quality and the frequency of AMI admissions at the Intensive Cardiologic Clinic of St. Marina University Hospital, Varna was determined in the period between October 2004 and December 2005. The samples were taken at four points of the Regional Inspectorate of Protection and Control of Public Health, Varna. Pollutants such as general and fine particulate matter with particle diameters up to 10 µg/m3 (FPM10), ozone, nitrogen oxide, dioxide and total general nitrogen oxides, and mean 24-hour values of meteorological parameters were monitored.


The independent influence of FPM10 on frequency of AMI hospitalizations is described using a linear regression model. In all combined methods, the standardized Beta coefficients are higher than that of isolated FPM action. In combination with the meteorological parameters model, the influence of FPM is increased, and air movement velocity is a protector. The combination of FPMs with the other pollutants-ozone, non-methane hydrocarbons, nitrogen dioxide, total hydrocarbons and carbon oxide is connected with the highest risk for AMI.


Fine particulate matter Meteorological parameters Acute myocardial infarction 


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Copyright information

© Versita Warsaw and Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Emiliya Karaslavova
    • 1
  • Teodora Dimitrova
    • 2
  • Nikolai Donchev
    • 3
  • Bilyana Teneva
    • 4
  • Pavel Timonov
    • 5
  1. 1.Faculty of BiologyUniversity of Plovdiv „Paisii Hilendarski”PlovdivBulgaria
  2. 2.Department of Medico-biological sciencesMedical University — VarnaVarnaBulgaria
  3. 3.Vascular SurgeryMBAL St AnnaVarnaBulgaria
  4. 4.Gastroenterology and Hepatology DepartmentMedical University — PlovdivPlovdivBulgaria
  5. 5.Department of Pathological Anatomy and Forensic MedicineMedical University — PlovdivPlovdivBulgaria

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