Progressive course of isolated splenic myeloid sarcoma
- 88 Downloads
A previously healthy 40-year-old male presented with a 2-week history of fever and abdominal discomfort that was resistant to empirical broad-spectrum antibiotic treatment. The patient’s blood cell count and complete biochemical panel was normal, except for an increased lactate dehydrogenase level. Ultrasonography and computed tomography of the abdomen showed a large, soft tissue mass had infiltrated superior part of the spleen. Splenectomy with total tumor mass removal were performed. The pathological examination of the tumor tissue confirmed diagnosis of isolated myeloid sarcoma with monoblastic differentiation. Despite intensive antileukemic therapy, patient died four months after diagnosis was established.
KeywordsSpleen Isolated myeloid sarcoma
Unable to display preview. Download preview PDF.
- Pileri SA, Orayi A, Falini B: Myeloid sarcoma. In Swerdlow S, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (eds) WHO classification of tumours of haematopoetic and lymphoid tissues. Lyon, IARC, 2008, pp 140–141Google Scholar
- Burns A. Observation of surgical anatomy, head and neck. Edinburgh: Thomas Royce and co;1811, pp 364–366Google Scholar
- King A. A case of chloroma. Monthly J med 1853;17:97Google Scholar
- Rappaport H. Tumors of the hematopoetic system. Armed Forces Inst Pathol 1966; 241–243Google Scholar
- Hutchinson RE, Kurec AS, Davey FR. Granulocytic sarcoma. Clin Lab Med. 1990; 10; 889–901Google Scholar
- Paydas S, Zorludemir S, Ergin M. Granulocytic sarcoma: 32 cases and review of the literature. Leuk Lymphoma. 2006; 47(12)Google Scholar
- Chevallier P, Labopin M, Cornelissen J, Socié G, Rocha V, Mohty M; ALWP of EBMT. Allogeneic hematopoietic stem cell transplantation for isolated and leukemic myeloid sarcoma in adults: a report from the Acute Leukemia Working Party of the European group for Blood and Marrow Transplantation. Haematologica.2011;96(9):1391–1394PubMedCrossRefGoogle Scholar