Central European Journal of Medicine

, Volume 8, Issue 2, pp 237–243 | Cite as

Subcutaneous adipose tissue measurements and better metabolic prediction

  • Petar Ristic
  • Dubravko Bokonjic
  • Vladimir Zivkovic
  • Vladimir Jakovljevic
  • Marija Zdravkovic
  • Janko Pejovic
  • Dragana Ristic
  • Jovan Mladenovic
Research Article


The aim of the study was to establish the importance of an additional measurement of subcutaneous adipose tissue thickness (SAT) on a predetermined position on the waistline, and its relation to waist measurements as an improvement of metabolic prediction in equally obese subjects. One hundred and forty two consecutive patients were enrolled in the study: stratified by weight as normal (body mass index — BMI 20–25 kg/m2), overweight (BMI 25–30 kg/m2) and obese (BMI >30 kg/m2); and by fasting glucose level as normoglycemic, impaired fasting glucose (IFG), or with type 2 diabetes mellitus (T2DM). SAT was measured in relaxed expiration, 3 cm left of the umbilicus, with ultrasound. Fasting blood samples for glucose, insulin and HbAlc were taken. Waist circumference was slightly higher in the IFG (112.8 cm) and normoglycemic groups (115.62 cm), compared to T2DM (108.15 cm). The T2DM group had a lower average SAT (2.7 cm) than both the IFG group (3.4 cm, p<0.01) and the normoglycemic group (4.2cm, p=0.001). The homeostatic model of assessment for insulin resistance (HOMA IR) was the lowest in normoglycemic and the highest in IFG group. Waistline radius to SAT ratio provides better insight into the deterioration of glucose metabolism than standard anthropometric markers of abdominal obesity in equally obese patients.


Subcutaneous adipose tissue thickness Glucose metabolism deterioration Central adiposity 


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Copyright information

© Versita Warsaw and Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Petar Ristic
    • 1
  • Dubravko Bokonjic
    • 2
  • Vladimir Zivkovic
    • 3
  • Vladimir Jakovljevic
    • 3
  • Marija Zdravkovic
    • 4
  • Janko Pejovic
    • 5
  • Dragana Ristic
    • 6
  • Jovan Mladenovic
    • 7
  1. 1.Endocrinology ClinicMilitary Medical AcademyBelgradeSerbia
  2. 2.Centre for Poisoning ControlMilitary Medical AcademyBelgradeSerbia
  3. 3.Department of Physiology, Faculty of MedicineUniversity of KragujevacKragujevacSerbia
  4. 4.Department of CardiologyUniversity Hospital Medical Center “Bezanijska kosa”, Faculty of Medicine, University of BelgradeBelgradeSerbia
  5. 5.Dept. of BiochemistryMilitary Medical AcademyBelgradeSerbia
  6. 6.Eye ClinicMilitary Medical AcademyBelgradeSerbia
  7. 7.Institute of EpidemiologyMilitary Medical AcademyBelgradeSerbia

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