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Central European Journal of Medicine

, Volume 7, Issue 4, pp 525–528 | Cite as

Chronic Idiopathic Thrombocytopenic Purpura in children: predictive factors and outcome

  • Paola Coccia
  • Antonio Ruggiero
  • Giorgio Attinà
  • Giuseppe Cerchiara
  • Andrea Battista
  • Roberta Arena
  • Maria Scalzone
  • Nadia Puma
  • Vita Ridola
  • Riccardo Riccardi
Review Article
  • 78 Downloads

Abstract

Idiopathic thrombocytopenic purpura (ITP) is the most common cause of acquired thrombocytopenia in children. In 20% of cases, this condition is classified as chronic when the thrombocytopenia is persistent 6 months after diagnosis. The aim of the present study is to identify the potential factors correlating with a favorable outcome in patients with chronic ITP. Some 71 patients affected by ITP were retrospectively analyzed. Results show a higher rate of spontaneous recovery that is statistically significant for patients with platelet count at diagnosis <20,000/µL. These observations suggest the possibility to delay or avoid aggressive surgical treatment for these patients.

Keywords

Idiopathic thrombocytopenic purpura Spontaneous remission Prognosis Children 

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Copyright information

© Versita Warsaw and Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Paola Coccia
    • 1
  • Antonio Ruggiero
    • 1
  • Giorgio Attinà
    • 1
  • Giuseppe Cerchiara
    • 1
  • Andrea Battista
    • 1
  • Roberta Arena
    • 1
  • Maria Scalzone
    • 1
  • Nadia Puma
    • 1
  • Vita Ridola
    • 1
  • Riccardo Riccardi
    • 1
  1. 1.Division of Pediatric OncologyCatholic UniversityRomaItaly

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