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Central European Journal of Medicine

, Volume 7, Issue 1, pp 91–94 | Cite as

Double-trouble: An unusual case of two simultaneous arterial thromboses in thrombophilia

  • Mirjana Krotin
  • Marija Zdravkovic
  • Danica Popovic-Lisulov
  • Jelena Saric
  • Dusica Celeketic
  • Mirna Zaja
  • Darko Zdravkovic
Case report

Abstract

Multiple arterial and venous thromboses are usually related to thrombophilia or antiphospholipid syndrome. Recurrent pulmonary embolism strongly indicates the presence of genetic or acquired thrombophilic factors. Simultaneous double arterial in situ thromboses are unusual, even in thrombophilic conditions. Simultaneous occurrence of pulmonary embolism and cerebrovascular ischaemic insult are highly indicative of existence of patent foramen ovale. We present herein a patient with the double simultaneous arterial thromboses as the manifestation of thrombophilia (heterozygous for methylenetetrahydrofolate-reductase (MTHFR) C677T gene mutation). There was no patent foramen ovale suspected upon the patient’s admittance to hospital. To the best of our knowledge there have been no similar cases presented to date.

Keywords

Arterial thrombosis Simultaneous thromboses C677T methylenetetrahydrofolate reductase gene mutation Therapy Diagnosis 

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Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Mirjana Krotin
    • 1
    • 3
  • Marija Zdravkovic
    • 1
    • 3
  • Danica Popovic-Lisulov
    • 1
  • Jelena Saric
    • 1
  • Dusica Celeketic
    • 2
    • 3
  • Mirna Zaja
    • 1
  • Darko Zdravkovic
    • 1
    • 3
  1. 1.Department of CardiologyUniversity Clinical Hospital Center Bezanijska KosaBelgradeSerbia
  2. 2.Department of HaematologyUniversity Clinical Hospital Center ZemunBelgradeSerbia
  3. 3.Faculty of MedicineUniversity of BelgradeBelgradeSerbia

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