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The weight change impact on metabolic syndrome: a 17-year follow-up study

  • Research Article
  • Published:
Central European Journal of Medicine

Abstract

Introduction: Data on long-term patterns of weight change in relation to the development of metabolic syndrome (MetS) are scarce. The aim of the study was to evaluate the impact of weight change on the risk of MetS in men. Material and Methods: Prospective longitudinal observation (17.9 ± 8.1 years) of apparently healthy 324 men aged 18–64 years. Metabolic risk was assessed in weight gain (⩾ 2.5 kg), stable weight (> −2.5 kg and < 2.5 kg) and weight loss (⩽ −2.5 kg) groups. Adjusted relative risk (RR) of MetS was analyzed using multivariate logistic regression. Results: The prevalence of MetS over follow-up was 22.5%. There was a strong relationship between weight gain and worsening of MetS components among baseline overweight men. Long-term increase in weight was most strongly related with the risk of abdominal obesity (RR=7.26; 95% CI 2.98–18.98), regardless of baseline body mass index (BMI). Weight loss was protective against most metabolic disorders. Leisure-time physical activity (LTPA) with energy expenditure > 2000 metabolic equivalent/min/week was associated with a significantly lower risk of MetS. Conclusions: Reducing weight among overweight and maintaining stable weight among normal-weight men lower the risk of MetS. High LTPA level may additionally decrease the metabolic risk regardless of BMI.

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Authors and Affiliations

  1. Department of Social and Preventive Medicine, Medical University of Lodz, Lodz, 90-647, Poland

    Magdalena Kwaśniewska, Dorota Kaleta, Elżbieta Dziankowska-Zaborszczyk & Wojciech Drygas

  2. Department of Sports Medicine, Medical University of Lodz, Lodz, 90-647, Poland

    Anna Jegier

  3. Department of Geriatrics, Medical University of Lodz, Lodz, 90-647, Poland

    Tomasz Kostka

  4. Department of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, Institute of Cardiology, Warsaw, 04-628, Poland

    Wojciech Drygas

Authors
  1. Magdalena Kwaśniewska
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  2. Dorota Kaleta
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  3. Anna Jegier
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  4. Tomasz Kostka
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  5. Elżbieta Dziankowska-Zaborszczyk
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  6. Wojciech Drygas
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Correspondence to Magdalena Kwaśniewska.

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Kwaśniewska, M., Kaleta, D., Jegier, A. et al. The weight change impact on metabolic syndrome: a 17-year follow-up study. cent.eur.j.med 6, 788–794 (2011). https://doi.org/10.2478/s11536-011-0093-2

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  • DOI: https://doi.org/10.2478/s11536-011-0093-2

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