Central European Journal of Medicine

, Volume 6, Issue 4, pp 379–385 | Cite as

Predictive values of metabolic syndrome in children

  • Ivana Vorgučin
  • Nada Naumović
  • Jovan Vlaški
  • Dragan Katanić
  • Georgios Konstantinidis
Research Article


Metabolic syndrome is a clinical term encompassing risk factors (obesity, insulin resistance, dyslipidemia and hypertension), which yield an increased risk for the development of diabetes mellitus type 2 and cardiovascular disorders in adolescence. Two sets of criteria for diagnosing metabolic syndrome were applied, the criteria for adults, specifically adapted for children, and the criteria defined by the International Diabetes Federation (IDF). A reliability analysis was conducted; sensitivity (SE), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV) of applying certain criteria of both definitions of metabolic syndrome. Metabolic syndrome in adolescents was diagnosed much more frequently using the specific criteria (41%) in comparison to the IDF criteria (22%). Using the specific criteria for children and adolescents, it was established that the HDL cholesterol was the most specific and had the largest PPV. Using the IDF criteria for diagnosing metabolic syndrome, the reliability analysis established that the highest PPV was recorded with the elevated level of triglycerides. The specific criteria have been found to be more efficient in diagnosing metabolic syndrome in adolescents. The highest predictive value was displayed by dyslipidemic disorders, hypertriglyceridemia and hypo HDL cholesterolemia.


Metabolic syndrome Children Predictive value 


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Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Ivana Vorgučin
    • 1
  • Nada Naumović
    • 2
  • Jovan Vlaški
    • 1
  • Dragan Katanić
    • 1
  • Georgios Konstantinidis
    • 1
  1. 1.Institute for child and youth health care of VojvodinaNovi SadSerbia
  2. 2.Department of physiologyFaculty of medicine Novi SadNovi SadSerbia

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