Central European Journal of Medicine

, Volume 6, Issue 3, pp 284–288 | Cite as

Sarcomatoid carcinoma of the urinary bladder and concomitant abdominal aortic aneurysm: a case report and literature review

  • Simona Di Francesco
  • Salvatore Magnasco
  • Raffaele L. Tenaglia
Research Article


We report the diagnostic evaluation, management, and intermediate-term outcomes of a rare variant of bladder cancer and concomitant Abdominal Aortic Aneurysm. A 62 year old male with gross haematuria and Abdominal Aortic Aneurysm was admitted to our hospital. Cystoscopy revealed a large bulky mass occupying the posterior bladder wall. The tumor was transurethrally resected and its histology showed a Sarcomatoid Carcinoma of the urinary bladder. Due to the aggressive behavior of the tumor and the risk of aneurysm rupture, concomitant endovascular exclusion of Aneurysm, total cystectomy with urinary diversion was performed. 12 months after radical surgery the patient was alive without any local recurrence, distant metastasis, and thrombosis of iliac axis. To our knowledge this study is the first report to describe data on the diagnostic evaluation, Management, and intermediate-term outcomes in Sarcomatoid carcinoma and Concomitant Abdominal Aortic Aneurysm. Multi-institutional collaboration is important to perform clinical trials of adequate sample size to design more effective treatments for these aggressive cancers in the presence of Concomitant Abdominal Aortic Aneurysm.


Bladder Cancer Sarcomatoid Carcinoma Abdominal Aortic Aneurysm Endoprosthesis 


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  1. [1]
    Dahm P., Gschwend J. E. Malignant Non-Urothelial Neoplasms of the Urinary Bladder: A Review. Eur Urol 2003; 44: 672–681PubMedCrossRefGoogle Scholar
  2. [2]
    Torenbeek R., Blomjous C. M., De Bruin P. C., Newling D. W., Meijer C. J.: Sarcomatoid carcinoma of the urinary bladder. Am. J. Surg. Pathol. 1994; 18:241PubMedCrossRefGoogle Scholar
  3. [3]
    Lopez-Beltran A., Pacelli A, Rothenberg H. J. et al. Carcinosarcoma and sarcomatoid carcinoma of the bladder: clinicopathological study of 41 Cases. J Urol. 1998; 159:1497–1503PubMedCrossRefGoogle Scholar
  4. [4]
    Ikegami H., Iwasaki H., Ohjimi Y., Takeuchi T., Ariyoshi A., Kikuchi M. Sarcomatoid carcinoma of the Urinary Bladder: a clinicopathologic and immunohistochemical analysis of 14 Patients. Hum Pathol 2000; 31:332–340PubMedCrossRefGoogle Scholar
  5. [5]
    Antonelli A., Simeone C., Ferrari V., Tardanico R., Cunico Cosciani S. Durable and complete remission of a metastatic bladder sarcomatoid carcinoma with chemotherapic and surgical treatments. Arch. Ital. Urol. Androl. 2006; 78:67–70PubMedGoogle Scholar
  6. [6]
    Lopez-Beltran A., Requena M. J., Cheng L., Montironi R. Pathological variants of invasive bladder cancer according to their suggested clinical significance BJU Int. 2008; 101:275–281PubMedCrossRefGoogle Scholar
  7. [7]
    Sung M. T., Wang M., MacLennan G.T. et al. Histogenesis of sarcomatoid urothelial carcinoma of the urinary bladder: evidence for a common clonal origin with divergent differentiation J Pathol. 2007; 211:420–430PubMedCrossRefGoogle Scholar
  8. [8]
    Lopez-Beltran A., Requena M. J., Liang C. and Montironi R. Pathological variants of invasive bladder cancer according to their suggested clinical significance. BJU Int. 2007; 101:275–281PubMedCrossRefGoogle Scholar
  9. [9]
    Arenas L. F., Fontes D. A., Pereira E. M., Hering F. L. Sarcomatoid carcinoma with osseous differentiation in the bladder Int. Braz J Urol 2006; 32:563–565Google Scholar
  10. [10]
    Black P. C., Brown G. A., Dinney C. P, The impact of variant histology on the outcome of bladder cancer treated with curative intent. Urol. Oncol 2009; 27:3–7PubMedGoogle Scholar
  11. [11]
    Pagano S., Ruggeri P., Franzoso F., Brusamolino R., Unusual renal cell carcinoma metastasis to the gallbladder Urol. 1995; 45:867–869Google Scholar
  12. [12]
    Grego F., Lepidi S., Bassi P. et al. Simultaneous surgical treatment of abdominal aortic aneurysm and carcinoma of the bladder. J Vasc Surg 2003; 37:607–614PubMedCrossRefGoogle Scholar
  13. [13]
    Mearini L., Zucchi A., Pizzirusso G., Vivaacqua C., Mearini L. Incidence and evolution of aortic aneurysm in patient with bladder cancer Arch. Ital. Urol. Androl. 2004; 76:80–82Google Scholar

Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Simona Di Francesco
    • 1
  • Salvatore Magnasco
    • 2
  • Raffaele L. Tenaglia
    • 1
  1. 1.Department of Medicine and Aging Science, Section of Clinical Urology and AndrologyUniversity “G. D’Annunzio” Chieti-PescaraChietiItaly
  2. 2.Department of Pathological AnatomyUniversity “G. D’Annunzio” Chieti-PescaraChietiItaly

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