Central European Journal of Medicine

, Volume 5, Issue 4, pp 513–519 | Cite as

Prognostic factors in patients who have survived myocardial infarction

  • Emina D. Aleksić
  • Radmila Lj. Stamenković
  • Dragan B. Đorđević
  • Gordana D. Lazarević
  • Duško B. Vulić
  • Ivan S. Tasić
Research Article


Patients who have survived myocardial infarction (MI), compared to the general population, have an increased risk of reinfarction, myocardial revascularization, and death. In this study we investigated the prognostic significance of the predictors of the risk for adverse coronary events in 118 patients, both male and female, with a confirmed diagnosis of MI in the last 3 years. The predictors of reinfarction, revascularization and death in patients who survived MI were: poor adherence to hypolipemics (hazard ratio [HR] 3.06, p=0.006), physical inactivity (HR 2.22, p=0.056), the number of variable risk factors (HR 1.29, p=0.025), and age (HR 1.06, p=0.007). After the inclusion of the invariable risk factors in the model of multivariant analysis, the following factors were singled out as significant predictors of the risk: gender (HR 3.86, p=0.0015), physical inactivity (HR 2.38, p=0.007), change in the level of triglycerides (HR 1.49, p=0.040), change in the number of variable risk factors (HR 1.41, p=0.0007), and age (HR 1.05, p=0.009). A 3-year follow-up of the patients who survived the first MI and who were enrolled in this study of secondary prevention demonstrated that physical inactivity, the number of variable risk factors and age significantly contributed to an increased risk of reinfarction, revascularization, and death.


Myocardial infarction Adverse coronary events Independent prognostic factors 


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Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Emina D. Aleksić
    • 1
  • Radmila Lj. Stamenković
    • 2
  • Dragan B. Đorđević
    • 3
  • Gordana D. Lazarević
    • 4
  • Duško B. Vulić
    • 5
  • Ivan S. Tasić
    • 3
  1. 1.Department of PediatricsHealth Care Centre PirotPirotSerbia
  2. 2.Emergency Health Care DepartmentHealth Care Centre LeskovacLeskovacSerbia
  3. 3.Institute for the Tnerapy and Rehabilitation „Niška Banja”Niška BanjaSerbia
  4. 4.Clinic of CardiologyClinical Centre NišNišSerbia
  5. 5.Center for medical research and development health careBanja LukaBosnia and Herzegovina

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