Central European Journal of Medicine

, Volume 5, Issue 4, pp 475–477 | Cite as

Tuberculous spondylitis in patients with end-stage renal disease undergoing chronic hemodialysis therapy — Report of two cases

  • Kosta Kostov
  • Plamen Yovchevski
  • Ivan Petrov
Case Report


Tuberculous spondylitis is more common in patients with chronic renal failure who receive hemodialysis because of their abnormal T-cell-mediated immunity. It frequently poses both diagnostic and therapeutic challenges. We describe two cases of tuberculous spondylitis in patients undergoing chronic hemodialysis therapy. They are IFN-γ assay diagnosed (QuantiFERON-TB Gold) and conservatively treated. Our cases suggest that IFN-γ assays equip clinicians with more accurate tools for tuberculosis control. A combination of T-SPOT.TB testing and MRI assessment may be the accurate method to diagnose tuberculous spondylitis in patients with end-stage renal disease.


Tuberculous spondylitis End-stage renal disease IFN-γ assay Magnetic resonance imaging Antituberculous treatment 


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Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  1. 1.Departments of NeurologyMinistry of InteriorSofiaBulgaria
  2. 2.Nephrology of Medical InstituteMinistry of InteriorSofiaBulgaria

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