Central European Journal of Medicine

, Volume 5, Issue 2, pp 172–175 | Cite as

Congenital heart disease and pulmonary tuberculosis

  • Rana Olguntürk
  • F.Sedef Tunaoğlu
  • Levent Gökgöz
  • Leyla Memiş
  • Serdar Kula
Case Report


A 13-year-old boy with atrial septal defect and tricuspid valve abnormality was reported. He had crepitan ralles and signs of heart failure. He was treated with digital, diuretic and antimicrobial therapies. After clinical improvement he underwent surgery. The atrial septal defect was closed, and ringplasty was applied to the tricuspid valve. After the operation, he could not be extubated because of respiratory failure. On the seventh day following the surgery, he developed pneumothorax and hyportension and died. Postmortem examination showed bilateral diffuse pulmonary tuberculosis. The aim of this report is to emphasise the association of tuberculosis and congenital heart disease.


Pulmonary tuberculosis Congenital heart disease Surgery 


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  1. [1]
    Mandalakas A.M., Starke J.R., Current concept of childhood tuberculosis, Semin. Pediatr. Infect. Dis., 2005, 16, 93–104CrossRefGoogle Scholar
  2. [2]
    Van der Merwe P.L., Kalis N., Schaaf H.S., Nel E.H., Gie R.P., Risk of pulmonary tuberculosis in children with congenital heart disease, Pediatr. Cardiol., 1995, 16, 172–5Google Scholar
  3. [3]
    Ifere Q.A., Aikhionbare H.A., Yusuf U., Congenital heart disease masking pulmonary tuberculosis in children, East. Afr. Med. J., 1989, 66, 414–8Google Scholar
  4. [4]
    Raviglione M.C., Snider D.E.J., Kochi A., Global epidemiology of tuberculosis: morbidity and mortality of a worldwide epidemic, JAMA., 1995,273, 220–6CrossRefPubMedGoogle Scholar
  5. [5]
    Kampmann B., Young D., Childhood tuberculosis: advances in immunopathogenesis, treatment and prevention, Curr. Opin. Infect. Dis., 1998,11, 331–5Google Scholar
  6. [6]
    Stead W.W., Senner J.W., Reddick W.T., Lofgren J.P., Racial differences in susceptibility to infection by mycobacterium tuberculosis, N. Eng. J. Med., 1990,322, 422–7CrossRefGoogle Scholar
  7. [7]
    Parisi M.T., Jensen M.C., Wood B.P., Pictorial review of the usual and unusual roentgen manifestations of childhood tuberculosis, Clin. Imag., 1994,18, 149–54CrossRefGoogle Scholar
  8. [8]
    Starke J.R., Jacobs R.F., Jereb J., Resurgence of tuberculosis in children, J. Pediatr., 1992,120, 839–55CrossRefGoogle Scholar
  9. [9]
    Tsao T.C, Juang Y.C., Tsai Y.H., Lan R.S., Lee C.H., Whole lung tuberculosis A disease with high mortality which is frequently misdiagnosed, Chest., 1992,101, 1309–11CrossRefPubMedGoogle Scholar
  10. [10]
    Starke J.R., Taylor-Watts K.T., Tuberculosis in the pediatric population of Houston, Texas, Pediatrics., 1989,84, 28–35Google Scholar
  11. [11]
    McMurray D.N., Mechanism of anergy in tuberculosis, Chest. 1980,77, 4–5CrossRefPubMedGoogle Scholar
  12. [12]
    Starke J.R., Childhood tuberculosis a diagnostic dilemma, Chest., 1993,104, 329–30CrossRefPubMedGoogle Scholar
  13. [13]
    Starke J.R., Pediatric tuberculosis: time for a new approach, Tuberculosis., 2003,83, 208–212CrossRefPubMedGoogle Scholar
  14. [14]
    Zar H.J., Hanslo D., Apolles P., Swingler G., Hussey G., Induced sputum versus gastric lavage for microbiological confirmation of pulmonary tuberculosis in infants and young children: a prospective study, Lancet., 2005,365,130–134CrossRefPubMedGoogle Scholar
  15. [15]
    Eamranond P., Jaramillo E., Tuberculosis in children: Reassessing the need for improved diagnosis in global control strategies, Int. J. Tuberc. Lung. Dis., 2001, 5, 594–603PubMedGoogle Scholar
  16. [16]
    Shingadia D., Novelli V., Diagnosis and treatment of tuberculosis in children, Lancet. Infect. Dis., 2003, 3, 624–32CrossRefPubMedGoogle Scholar
  17. [17]
    Pomputius WF 3rd., Rost J., Dennehy P.H., Carter E.J., Standartization of gastric aspirate technique improves yield in the diagnosis of tuberculosis in children, Pediatr. Infect. Dis. J.,1997,16, 222–6CrossRefPubMedGoogle Scholar
  18. [18]
    Sarode V.R., Datta B.N., Banerjee A.K., Banerjee C.K., Joshi K., Bhusnurmath B., Radotra B.D. et al., Autopsy finding and clinical review of 1000 cases, Hum. Pathol., 1993,24, 194–8CrossRefPubMedGoogle Scholar

Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Rana Olguntürk
    • 1
  • F.Sedef Tunaoğlu
    • 1
  • Levent Gökgöz
    • 2
  • Leyla Memiş
    • 3
  • Serdar Kula
    • 1
  1. 1.Department of Pediatric CardiologyGazi University, Medical FacultyAnkaraTurkey
  2. 2.Department of Cardiovascular SurgeryGazi University, Medical FacultyAnkaraTurkey
  3. 3.Department of PathologyGazi University, Medical FacultyAnkaraTurkey

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