Hypercalcemia: A rare cause of cerebral infarction

  • Shahzad Riyaz
  • James Tymms
Case Report


Hypercalcemia is a definite but rare cause of acute pancreatitis. It is often overlooked in the presence of more common etiological factors such as gallstones, alcohol and trauma. Cerebral infarction secondary to hypercalcemia has also been described. We have done a literature review to explore the possible pathological processes causing cerebral infarction in hypercalcemic patients.


Hypercalcemia Pancreatitis Stroke 


  1. [1]
    Fitz T.E., Hallman B.L., Mental changes associated with hyperparathyroidism, Arch. Intern. Med., 1952, 89, 547–51Google Scholar
  2. [2]
    Bostrom H., Alveryd A., Stroke in Hyperparathyroidism, Acta Med. Scand., 1972, 192, 299–308PubMedGoogle Scholar
  3. [3]
    Bartter F.C., The parathyroid gland and its relationship to diseases of the nervous system, Res. Nerv. Ment. Dis., 1953, 32, 1–20Google Scholar
  4. [4]
    Karpati G., Frame B., Neuropsychiatric disorders in primary hyperparathyroidism. Clinical analysis with review of the literature. Arch. Neurol., 1964, 10, 387–97PubMedGoogle Scholar
  5. [5]
    Walker G.L., Williamson P.M., Ravich R.B., Roche J., Hypercalcemia associated with cerebral vasospasm causing infarction, J. Neurol. Neurosurg. Psychiatry, 1980, 43, 464–7PubMedGoogle Scholar
  6. [6]
    Allen G.S., Gross C.J., Henderson L.M., Cerebral artery spasm, J. Neurosurg., 1976, 44, 585–93PubMedCrossRefGoogle Scholar
  7. [7]
    Edvinsson L., Brandt L., Andersson K.E., Bengtsson B., Effect of calcium antagonist on experimental constriction of human brain vessels, Surg. Neurol., 1979, 11, 327–30PubMedGoogle Scholar

Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  1. 1.Department of MedicineRoyal Albert Edward InfirmaryWigan, LancashireUnited Kingdom

Personalised recommendations