Abstract
Pyoderma gangrenosum is an inflammatory dermatosis of uncertain etiology, often associated with chronic inflammatory bowel or rheumatoid disease. It predominantly affects the skin. A systemic organ involvement caused by aseptic neutrophilic abscesses, however, fundamentally influences the prognosis.
A patient with idiopathic pyoderma gangrenosum insufficiently responded to a conventional immune suppressive therapy and the disease proceeded aggressively. During treatment with Infliximab, partial remission was achieved intermediately. However, a recurring endocarditis, led to a lethal outcome of this patient.
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Drinda, S., Oelzner, P., Codina Canet, C. et al. Fatal outcome of pyoderma gangrenosum with multiple organ involvement and partially responding to Infliximab. cent.eur.j.med 1, 306–312 (2006). https://doi.org/10.2478/s11536-006-0024-9
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DOI: https://doi.org/10.2478/s11536-006-0024-9