Abstract
In numerous recent papers plasma chemistry of non equilibrium plasma sources operating at atmospheric pressure has been linked to plasma medical effects including sterilization. In this paper we present a study of the effectiveness of an atmospheric pressure plasma source, known as plasma needle, in inhibition of the growth of biofilm produced by methicillin resistant Staphylococcus aureus (MRSA). Even at the lowest powers the biofilms formed by inoculi of MRSA of 104 and 105 CFU have been strongly affected by plasma and growth in biofilms was inhibited. The eradication of the already formed biofilm was not achieved and it is required to go to more effective sources.
Similar content being viewed by others
References
P. Cos, K. Toté, T. Horemans, L. Meas, Curr. Pharm. Des. 16, 2279 (2010)
U. Römling,, C. Balsalobre, J. Intern. Med. 272, 541 (2012)
Z. Lj. Petrović et al., Journal of Physics: Conference Series 356, 012001 (2012)
Z. Lj. Petrović et al., J. Serb. Chem. Soc. 77, 1689 (2012)
M. Moreau, N. Orange, M. G. J. Feuilloley, Biotechnol. Adv. 26, 610 (2008)
J. Goree, B. Liu, D. Drake, E. Stoffels, IEEE T. Plasma Sci. 34, 1317 (2006)
B. Kim, et al., Food microbial. 28, 9 (2011)
G. Fridman et al., Plasma Process. Polym. 4, 503 (2008)
T. Maisch et al., PloS One 7, e34610 (2012)
J. L. Zimmermann et al., New J. Phys. 14, 073037 (2012)
M. G. Kong et al., New J. Phys. 11, 115012 (2009)
M. Hee Lee et al., New J. Phys. 11, 115022 (2009)
S. G. Joshi et al., Am. J. Infect. Control 38, 293 (2010)
N. Puač et al., J. Phys. D Appl. Phys. 39, 3514 (2006)
S. Lazović et al., New J. Phys. 12, 083037 (2010)
N. Hoiby et al., Int. J. Oral. Sci. 3, 55 (2011)
T. J. Hannan et al., FEMS Microbiol. Rev. 36, 616 (2012)
C. J. Sanchez et al., BMC Infect. Dis. 13, 47 (2013)
N. K. Archer et al., Virulence 2, 445 (2011)
J. M. Mootz et al., Infect. Immun. 81, 3227 (2013)
K. D. Weltmann et al., Pure Appl. Chem. 82, 1223 (2010)
M. Laroussi, Plasma Process. Polym. 2, 391 (2005)
M. Moisan et al., Int. J. Pharmaceut. 226, 1 (2001)
U. Cvelbar, M. Mozetič, N. Hauptman, M. Klanjsek-Gunde, J. Appl. Phys. 106, 103303 (2009)
S. Manola, Z. Lj. Petrović, R. M. Jankov, In: M. Milosavljevic (Ed.), 16th SPIG XVI Summer School and International Symposium on the Physics of Ionized Gases, Serbia (Belgrade 1993) 285
K. Stapelmann, O. Kylián, B. Denis, F. Rossi, J. Phys. D: Appl. Phys. 41, 192005 (2008)
D. O’Connell et al., Appl. Phys. Lett. 98, 043701 (2011)
A. von Keudell et al., Plasma Process. Polym. 7, 327 (2010)
N. Philip et al., IEEE T. Plasma Sci. 30, 1429 (2002)
M. Y. Alkawareek et al., FEMS Immunol. Med. Microbiol. 65, 381 (2012)
E. Kvam, B. Davis, F. Mondello, A. L. Garner, Antimicrob. Agents Ch. 46, 2028 (2012)
R. Matthes et al., Plasma Process. Polym. 10, 161 (2013)
T. Maisch et al., J. Ind. Microbiol. Biot. 39, 1367 (2012)
O. G. Brakstad, K. Aasbakk, J. A. Maeland, J. Clin. Microbiol. 30, 1654 (1992)
Y. Kondo et al., Antimicrob Agents Chemother 41, 264 (2007)
I. Ćirković, Ph.D. thesis, University of Belgrade (Belgrade, Serbia, 2009)
G. Malović, N. Puač, S. Lazović, Z. Lj. Petrović, Plasma Sources Sci. T. 19, 034014 (2010)
I. E. Kieft and E. Stoffels, New J. Phys. 6, 149 (2004)
E. Stoffels, J. Flikweert, W. W. Stoffels, G. M. W. Kroesen, Plasma Sources Sci. T. 11, 383 (2002)
S. Stepanović et al., APMIS 115, 891 (2007)
A. G. Whittaker et al., J. Hosp. Infect. 46, 37 (2004)
H. Halfmann, N. Bibinov, J. Wunderlich, P. Awakowicz, J. Phys. D., Appl.Phys. 40, 4145 (2007)
Y. F. Hong et al., Lett. Appl. Microbiol. 48, 33 (2009)
K. Lee, K. H. Peak, W. T. Ju, Y. Lee, J. Microbiol. 44, 269 (2006)
H. Yu et al., J. Appl. Microbiol. 101, 1323 (2006)
M. H. Lee et al., New J. Phys. 11, 115022 (2009)
J. J. Cotter et al., J. Hosp. Infect. 78, 204 (2011)
A. Ghaffari, C. C. Miller, B. McMullin, A. Ghahary, Nitric oxide 14, 21 (2006)
D. O. Schairer, J. S. Chouake, J. D. Nosanchuk, A. J. Friedman, Virulence 3, 271 (2012)
A. Friedman et al., Virulence 2, 217 (2011)
G. Han et al., PloS One 4, e7804 (2009)
Author information
Authors and Affiliations
Corresponding authors
About this article
Cite this article
Miletić, M., Vuković, D., Živanović, I. et al. Inhibition of methicillin resistant Staphylococcus aureus by a plasma needle. centr.eur.j.phys. 12, 160–167 (2014). https://doi.org/10.2478/s11534-014-0437-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.2478/s11534-014-0437-z