Skip to main content
SpringerLink
Log in

Properties of naproxen ion-selective electrodes

  • Short Communication
  • Published:
Central European Journal of Chemistry

Abstract

Naproxen membrane electrodes based on different plasticizers and the quaternary ammonium salts (QASs) dimethyldidecylammonium bromide, methyltrioctylammonium chloride, or tetraoctylammonium chloride, were prepared. The following basic parameters were investigated for the optimal electrode: measurement range (10−4 − 10−1 mol L−1), slope of the linear range of the calibration curve (−58.3 mV decade−1), limit of detection (6.0 × 10−5 mol L−1), lifetime (2.5 months), dependence of the electrode potential on pH (5.5 − 9.0), reproducibility of potential (1.2 mV) and selectivity coefficients in relation to selected organic and inorganic anions. The electrode was utilized for determination of naproxen in tablets by the calibration curve method and the standard addition method.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. V. V. Cosofret, R. P. Buck, Crit. Rev. Anal. Chem. 1, 24 (1993)

    Google Scholar 

  2. R. I. Stefan, G. E. Baiulescu, Y. Hassan, Crit. Rev. Anal. Chem. 27, 307 (1997)

    Article  CAS  Google Scholar 

  3. Z. Z. Zhang, V. V. Cosofret, Selective Electrode Rev. 12, 35 (1990)

    CAS  Google Scholar 

  4. V. V. Cosofret, R. P. Buck, Pharmaceutical Applications of Membrane Sensors (CRC Press, Boca Raton, FL, 1992)

    Google Scholar 

  5. P. Solich, P. E. Macheras, M. A. Koupparis, J. Pharm. Sci. 84, 889 (1995)

    Article  CAS  Google Scholar 

  6. The Merck Index (Inc. Whitehouse Station, NY, 1996)

  7. J. K. Podlewski, A. Chwalibowska-Podlewska, Leki Wspólczesnej Terapii (PZWL, Warszawa, 1985)

    Google Scholar 

  8. British Pharmacopoeia, Vol. 1 (The Stationery Office, London, 1999)

  9. The United States Pharmacopeia, XXII (INC., Rockville MD, 1990)

  10. R. Dumkiewicz, K. Sykut, A. Kusak, Chem. Anal. (Warsaw) 37, 35 (1992)

    CAS  Google Scholar 

  11. R. Dumkiewicz, C. Wardak, K. Pokrzywa, Chem. Anal. (Warsaw) 44, 857 (1999)

    CAS  Google Scholar 

  12. Bunaciu, A. Grasu, H. Y. Aboul-Enein, Anal. Chim. Acta, 311, 193 (1995)

    Article  CAS  Google Scholar 

  13. J. Lenik, C. Wardak, B. Marczewska, Acta Poloniae Pharmaceutica, 63, 239 (2006)

    CAS  Google Scholar 

  14. R. I. Stefan, H. Y. Aboul-Enein, Anal. Lett. 29, 35 (1996)

    CAS  Google Scholar 

  15. H. Hopkala, G. Misztal, Pharmazie 51, 96 (1996)

    CAS  Google Scholar 

  16. M.N.M.P. Alcada, J.L.F.C. Lima, M.C.B.S.M. Montenegro, J. Pharm. Biomed. Anal. 10, 757 (1992)

    Article  CAS  Google Scholar 

  17. J. Lenik, R. Dumkiewicz, C. Wardak, B. Marczewska, Acta Polonia Pharmaceutica 59, 171 (2002)

    CAS  Google Scholar 

  18. G.N. Valsami, P.E. Macheras, Analyst 114, 387 (1989)

    Article  CAS  Google Scholar 

  19. A. O. Santini, J. E. Oliveira, H. R. Pezza, L. Pezza, J. Braz. Chem. Soc. 17, 785 (2006)

    Article  CAS  Google Scholar 

  20. J. Lenik, B. Marczewska, C. Wardak, Desalination 163, 77 (2004)

    Article  CAS  Google Scholar 

  21. V.P.Y. Gadzekpo, G.D. Christian, Anal. Chim. Acta 164, 279 (1984)

    Article  CAS  Google Scholar 

  22. Schwake, K. Camman, A. L. Smirnova, S. S. Levitchevm, V. L. Grekovich, Yu. G. Vlasov, Anal. Chim. Acta 19, 393 (1999)

    Google Scholar 

  23. F. Hofmeister, Arch. Exp. Patol. Pharmacol. 24, 247 (1888)

    Article  Google Scholar 

  24. R. Dumkiewicz, J. Lenik, Chem. Anal. (Warsaw) 46, 31 (2001)

    CAS  Google Scholar 

  25. E. Lindner, Y. Umezawa, Pure Appl. Chem. 80 (1) 85 (2008)

    Article  CAS  Google Scholar 

  26. Clarke’s Isolation and Identification of Drugs, 2nd edition (The Pharmaceutical Press, London, 1986)

Download references

Author information

Authors and Affiliations

  1. Faculty of Chemistry, Maria Curie-Skłodowska University, 20-031, Lublin, Poland

    Joanna Lenik, Cecylia Wardak & Barbara Marczewska

Authors
  1. Joanna Lenik
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Cecylia Wardak
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Barbara Marczewska
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Joanna Lenik.

About this article

Cite this article

Lenik, J., Wardak, C. & Marczewska, B. Properties of naproxen ion-selective electrodes. cent.eur.j.chem. 6, 513–519 (2008). https://doi.org/10.2478/s11532-008-0075-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2478/s11532-008-0075-7

Keywords

Search

Navigation