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The effect of substituents of immobilized Rh complexes on the asymmetric hydrogenation of acetophenone derivatives

  • Research Article
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Central European Journal of Chemistry

Abstract

Using a modified Augustine’s method variously substituted Rh complexes were anchored on Al2O3 support. The prepared catalysts were characterized by spectroscopic methods and were applied in the hydrogenation of several acetophenone derivatives (p-CF3-acetophenone, acetophenone, p-NH2-acetophenone). Enantioselective C=O hydrogenations were observed with reasonable activity and selectivity on all heterogenized complexes, e.e. up to 80%. At the same time the immobilized samples showed the advantages of the heterogeneous systems: easy handling and recyclability.

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Author information

Authors and Affiliations

  1. Department of Organic Chemistry, University of Szeged, 6720, Szeged, Hungary

    Ágnes Zsigmond & Suhsen Undrala

  2. Organic Catalysis Research Group of the Hungarian Academy of Sciences, University of Szeged, 6720, Szeged, Hungary

    Ferenc Notheisz

  3. Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, 1521, Budapest, Hungary

    Áron Szöllősy

  4. Department of Organic Chemistry, University of Pannonia, 8200, Veszprém, Hungary

    József Bakos

Authors
  1. Ágnes Zsigmond
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  2. Suhsen Undrala
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  3. Ferenc Notheisz
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  4. Áron Szöllősy
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  5. József Bakos
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Correspondence to Ágnes Zsigmond.

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Zsigmond, Á., Undrala, S., Notheisz, F. et al. The effect of substituents of immobilized Rh complexes on the asymmetric hydrogenation of acetophenone derivatives. cent.eur.j.chem. 6, 549–554 (2008). https://doi.org/10.2478/s11532-008-0056-x

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  • DOI: https://doi.org/10.2478/s11532-008-0056-x

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