Abstract
9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6-ylhydrazine was reacted with 2-acetylpyridine to give a Schiff base as a potential tridentate ligand. The reaction of this ligand with gallium chloride afforded complexes of 1:1 and 2:1 stoichiometry. The results of X-ray diffraction studies of the ligand and both gallium complexes are reported and compared with the data for a related gallium complex with a Schiff base obtained from 9-bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6-ylhydrazine and 2-hydroxybenzaldehyde.
Similar content being viewed by others
References
D.W. Zaharevitz, R. Gussio, M. Leost, A.M. Senderowicz, T. Lahusen, C. Kunick, L. Meijer, E.A. Sausville, Cancer Res. 59, 2566 (1999).
E.B. Skibo, X. Huang, R. Martinez, R.H. Lemus, W.A. Craigo, J. Med. Chem. 55, 5543 (2002).
C. Schultz, A. Link, M. Leost, D.W. Zaharevitz, R. Gussio, E.A. Sausville, L. Meijer, Kunick, J. Med. Chem. 42, 2909 (1999).
J. Trapp, A. Jochum, R. Meier, L. Saunders, B. Marshall C. Kunick, E. Verdin, P. Goekjian, W. Sippl, M. Jung, J. Med. Chem. 49, 7307 (2006)
W.F. Schmid, S. Zorbas-Seifried, R.O. John, V.B. Arion, M.A. Jakupec, A. Roller, M.S. Galanski, I. Chiorescu, H. Zorbas, B.K. Keppler, Inorg. Chem. 46, 3645 (2007).
W.F. Schmid, R.O. John, G. Muehlgassner, P. Heffeter, M.A. Jakupec, M.S. Galanski, W. Berger, V.B. Arion, B.K. Keppler, J. Med. Chem. 50, 6343 (2007).
A. Dobrov, V.B. Arion, N. Kandler, W. Ginzinger, M.A. Jakupec, A. Rufinska, N. Graf von Keyserlingk, M.S. Galanski, C. Kowol, B.K. Keppler, Inorg. Chem. 45, 1945 (2006).
Z. Otwinowski, W. Minor, In: C.W. Carter Jr., R.M. Sweet, (Eds.), Methods in Enzymology Vol. 276: Macromolecular Crystallography Part A (Academic Press, London, 1997), 307
G.M. Sheldrick, SHELXS-97, Program for Crystal Structure Solution, University of Goettingen, Goettingen (1997)
Sheldrick G. M., SHELXL-97, Program for Crystal Structure Refinement, University of Goettingen, Goettingen (1997)
A.J.C. Wilson (Ed.), International Tables for X-ray Crystallography Vol. C (Kluwer Academic Publishers, Dordrecht, 1992), Tables 4.2.6.8 and 6.1.1.4
A.L. Spek, J. Appl. Cryst. 36, 7 (2003).
Bruker, XP (Version 5.1), Bruker AXS Inc., Madison, Wisconsin, USA (1998)
A.W. Addison, T.N. Rao, J. Reedijk, J. van Rijn, G.C. Verschoor, J. Chem. Soc. Dalton Trans. 7, 1349 (1984).
K. Robinson, G.V. Gibbs, P.H. Ribbe, Science 172, 567 (1971).
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Ginzinger, W., Arion, V.B., Giester, G. et al. Synthesis and structural peculiarities of gallium Complexes with novel paullone derivatives. cent.eur.j.chem. 6, 340–346 (2008). https://doi.org/10.2478/s11532-008-0048-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.2478/s11532-008-0048-x