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Solvent reduced wittig olefination reactions with halo containing conjugated phosphoranes

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Central European Journal of Chemistry

Abstract

The Wittig reaction of carbaldehydes with alkoxycarbonylhalomethylidenetriphenylphosphoranes can be performed with ease in solventless systems. The analogous reaction of carbaldehydes with acylhalomethylidenetriphenylphosphoranes requires a small amount of solvent, such as chloroform, in order for the reaction to proceed. The products of the reaction are versatile precursors for further transformations, such as the Suzuki-Miyaura cross-coupling reaction.

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  1. Institute of Materials Chemistry and Engineering, Kyushu University, Kasuyga-shi, Fukuoka, 816-8580, Japan

    Thies Thiemann, Yasuko Tanaka, Keiko Ideta & Shuntaro Mataka

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  1. Thies Thiemann
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Thiemann, T., Tanaka, Y., Ideta, K. et al. Solvent reduced wittig olefination reactions with halo containing conjugated phosphoranes. cent.eur.j.chem. 4, 403–427 (2006). https://doi.org/10.2478/s11532-006-0024-2

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