Acta Parasitologica

, Volume 57, Issue 1, pp 99–100 | Cite as

Demodex mite infestation in patients with and without rheumatoid arthritis

  • Aleksandra Garbacewicz
  • Janusz Jaworski
  • Barbara Grytner-Zięcina
Research Note


In the present study we compared the prevalence of Demodex mites in patients with rheumatoid arthritis and in one control group involving individuals of similar mean age. From each person we epilated 3–4 lashes from each eyelid and examined them under a microscope to find Demodex mites. In total 147 patients were examined. The prevalence of Demodex mites was 33% in rheumatoid arthritis (RA) patients and 31% in the control group. Our results demonstrated that the prevalence of Demodex mites was similar in RA patients as compared to the control group.


Demodex mites rheumatoid arthritis 


  1. Ashack R.J., Frost M.L., Norins A.L. 1989. Papular pruritic eruption of Demodex folliculitis in patients with acquired immunodeficiency syndrome. Journal of the American Academy of Dermatology, 21, 306–307. DOI: 10.1016/S0190-9622(89)70182-1.PubMedCrossRefGoogle Scholar
  2. Bonnar E., Eustace P., Powell F.C. 1993. The Demodex mite population in rosacea. Journal of the American Academy of Dermatology, 28, 443–448. DOI: 10.1016/01909622(93)70065-2.PubMedCrossRefGoogle Scholar
  3. Bovenschen H.J., Tjioe M., Vermaat H., de Hoop D., Witteman B.M., Janssens R.W., Stoof T.J., Kerkhof P.C. 2006. Induction of eruptive benign melanocytic naevi by immune suppressive agents, including biologicals. British Journal of Dermatology, 154, 880–884. DOI: 10.1111/j.1365-2133.2006.07189.x.PubMedCrossRefGoogle Scholar
  4. Czepita D., Kuźna-Grygiel W., Kosik-Bogacka D. 2005. Investigations on the occurrence as well as the role of Demodex folliculorum and Demodex brevis in the pathogenesis of blepharitis. Klinika Oczna, 107, 80–82.PubMedGoogle Scholar
  5. Damian D., Rogers M. 2003. Demodex infestation in a child with leukaemia: treatment with ivermectin and permethrin. International Journal of Dermatology, 42, 724–726. DOI: 10.1046/j.1365-4362.2003.01916.x.PubMedCrossRefGoogle Scholar
  6. Desch C., Nutting W.B. 1972. Demodex folliculorum (Simons) and D. brevis Akbulatova of man: redescription and reevaluation. Journal of Parasitology, 8, 169–177. DOI:10.2307/3278267.Google Scholar
  7. Garbacewicz A., Twarowska J., Grytner-Zięcina B. 2010. Demodex infection in different groups in the population of Warsaw. In: (Eds. A. Buczek and C. Błaszak) Arthropods. Ecological and pathological aspects of parasite — host relationships. Akapit, Lublin, 57–64.Google Scholar
  8. Herron M.D., O’Reilly M.A., Vanderhooft S.L. 2005. Refractory Demodex folliculitis in five children with acute lymphoblastic leukemia. Pediatric Dermatology, 22, 407–411. DOI: 10.1111/j.1525-1470.2005.00103.x.PubMedCrossRefGoogle Scholar
  9. Humiczewska M., Kuźna W., Hermach U. 1994. Frequency of occurrence of symptomatic and asymptomatic eyelids demodecosis among the inhabitants of Szczecin. Wiadomości Parazytologiczne, 40, 69–71.PubMedGoogle Scholar
  10. Ciftci I.H., Dundar U., Cetinkaya Z., Kulac M., Kiyildi N., Turel A., Evcik D., Kavuncu V. 2007. Demodex folliculorum in patients with rheumatoid arthritis. Acta Parasitologica, 52, 70–73. DOI: 10.2478/s11686-007-0002-7.CrossRefGoogle Scholar
  11. Ivy S.P., Mackall C.L., Gore L., Gress R.E., Hartley A.H. 1995. Demodicidosis in childhood acute lymphoblastic leukaemia: an opportunistic infection occurring with immunosuppression. Journal of Pediatrics, 127, 751–754. DOI: 10.1016/S0022-3476(95)70168-0.PubMedCrossRefGoogle Scholar
  12. Jansen T., Kastner U., Kreuter A., Altmeyer P. 2001. Rosacea-like demodicidosis associated with acquired immunodeficiency syndrome. British Journal of Dermatology, 144, 139–142. DOI: 10.1046/j.1365-2133.2001.03794.x.PubMedCrossRefGoogle Scholar
  13. Lipsky P.E., van der Heijde D.M., St Clair E.W., Furst D.E., Breedveld F.C., Kalden J.R., Smolen J.S., Weisman M., Emery P., Feldmann M., Harrman G.R., Maini R.N. 2000. Infliximab and Methotrexate in the treatment of Rheumatoid Arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. New England Journal of Medicine, 343, 1594–1602. DOI: 10.1056/nejm2000113034 32202.PubMedCrossRefGoogle Scholar

Copyright information

© © Versita Warsaw and Springer-Verlag Wien 2012

Authors and Affiliations

  • Aleksandra Garbacewicz
    • 1
  • Janusz Jaworski
    • 2
  • Barbara Grytner-Zięcina
    • 1
  1. 1.Department of General Biology and ParasitologyMedical University of WarsawWarsawPoland
  2. 2.NZOZ ReumatikaWarsawPoland

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