Central European Journal of Medicine

, Volume 3, Issue 4, pp 453–458 | Cite as

Clinicopathological features and survival rates of patients with renal cell carcinoma under 50 years of age

  • Ali Fuat AtmacaEmail author
  • Ömer Bayrak
  • Olcay Kandemir
  • Ege Can Şerefoğlu
  • Ílke Evrim Çulha
  • Abdullah Erdem Canda
  • M. Derya Balbay
Research Manuscript


We analyzed the clinicopathological features and survival rates of the patients with renal cell carcinoma younger than 50 years old. Between 2004 and 2007, 28 patients between 19–49 years underwent surgery for renal cell carcinoma. Presenting symptoms, type of the surgery performed, postoperative outcomes and duration of follow-up were recorded. Mean age was 41.5±7.6 years and 75% of patients were male. The tumor was symptomatic in 19(67.9%) and incidental in 9(32.1%) patients. Radical nephrectomy and nephron-sparing surgery were performed in 18(64.3%) and 10(35.7%) patients, respectively. The most common histologic type was clear cell(67.9%). The mean tumor diameters were 3.5±0.95 and 7.4±5.2 cm in the incidental and symptomatic groups, respectively(p=0.035). Incidentally discovered tumors and tumors treated by NSS did not include Fuhrman grade 4. There were no differences regarding pathological stage and Fuhrman grades when patients were grouped according to their symptomatology(p=0.242 and p=0.265, respectively). Overall mortality was 17.9%(n=5) whereas 4 patients(14.3%) died because of cancer. The mean survival was 30.6 months and cancer specific survival rate was 85.2%. Most of the tumors in this age group were symptomatic and most common histologic subtype was clear cell carcinoma. Incidentally discovered tumors had statistically significant lower tumor size.


Adult Renal cell carcinoma Symptoms Pathology 


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Copyright information

© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Ali Fuat Atmaca
    • 1
    Email author
  • Ömer Bayrak
    • 3
  • Olcay Kandemir
    • 2
  • Ege Can Şerefoğlu
    • 1
  • Ílke Evrim Çulha
    • 2
  • Abdullah Erdem Canda
    • 1
  • M. Derya Balbay
    • 1
  1. 1.1st Urology ClinicAnkara Ataturk Training and Research HospitalAnkaraTurkey
  2. 2.1st Pathology ClinicAnkara Ataturk Training and Research HospitalAnkaraTurkey
  3. 3.Department Of UrologyFatih Unıversıty Medical SchoolAnkaraTurkey

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