Abstract
We conformed the age- and sex-specific onset rates of SLE in three series from the United States, Netherland and Japan to the Weibull distribution. It was shown that all sample distributions were conformed to the distribution except for the first decade of age. In addition, it was observed on the Weibull probability paper that all distributions except the one for the American male SLE were displayed parallelly with nearly the same slope. It was not reasonable to explain the etiology of the disease with the random failure model simply because of a good fit obtained by the Weibull distribution. It was considered however that the fact that there were remarkable similarity on the shape among distributions from the three countries suggested the empirical distribution derived in this paper to be be used as provisional reference until more accurate statistics would be available.
Similar content being viewed by others
References
Baart de la Faille-Kuyper, E.H. (1969). Lupus erythematosus. An immunohistochemical and clinical study of 485 patients: Grafisch Bedrijf Schotanus & Jens, Utrecht N.V.
Burch, P.R.J. (1966). Spontaneous auto-immunity: Equations for age-specific prevalence and initiation-rates; J. Theoret. Biol. 12, 397–409.
Burch, P.R.J. and Rowell, N.R. (1963). Autoimmunity. Etiological aspects of chronic discoid and systemic lupus erythematosus, systemic sclerosis, and Hashimoto’s thyroiditis. Some immunological implications: Lancet. 2, 507–513.
Burch, P.R.J. and Rowell, N.R. (1965) Systemic lupus erythematosus. Etiological aspects; Amer. J. Med. 38. 793–801.
Burch, P.R.J. and Rowell. N.R. (1970). Lupus erythematosus. Analysis of the sex and age distributions of the discoid and systemic forms of the disease in different countries; Acta Dermatovener. (Stockholm) 50, 293–301.
Burnet, F.M. (1965). Somatic mutation and chronic disease: Brit Med. J. 1, 338–342.
Miyahara, H., Takeuchi, A., Yamagami, J. and Dumae, A. (1981). SLE shohatsu-nenrei-bunpu no kokusai hikaku (The age- and sex-distributions of SLE in Japan, the United States and Netherland); Progress report of the research group of auto immune disease (Y. Hormchi, ed.), 323–329. The Ministry of Health and Welfare.
Öfjiu, M., Miyawaki, S., Ohhira, M. and Ohhara, K. (1974). SLE Zenkoku Jittai Dai-niji-chosa Hokoku (Report of the second nationwide survey of SLE in Japan): Progress report of the research group of SLF. (M. Ofuji, ed.). 53–120, The Ministry of Health and Welfare.
Sörifu-Tökei-Kvoku (1974). Population by single years of age (1920 73); Report of the population census in Japanese statistics yearbook, 24, 24–25.
World Health Organization (1959). Annual epidemiological and vital statistics; Geneva.
Author information
Authors and Affiliations
About this article
Cite this article
Miyahara, H., Domae, A. The Age- And Sex-Distributions of Systemic Lupus Erythematosus in Japan, the United States and Netherland. Behaviormetrika 9, 17–26 (1982). https://doi.org/10.2333/bhmk.9.12_17
Received:
Published:
Issue Date:
DOI: https://doi.org/10.2333/bhmk.9.12_17