Breast Cancer

, Volume 13, Issue 3, pp 260–265 | Cite as

Effect of mechanical closure of dead space on seroma formation after Breast surgery

  • Katsumasa KuroiEmail author
  • Kojiro Shimozuma
  • Tetsuya Taguchi
  • Hirohisa Imai
  • Hiroyasu Yamashiro
  • Shozo POhsumi
  • Shinya Saito
Review Article


Seroma, a collection of serous fluid, is the most common problem after breast surgery. The aim of this study was to review the effect of mechanical closure of dead space on seroma formation after breast surgery. There are two mechanical methods for closure of the dead space beneath skin flaps: compression by external pressure, and fixation of the flaps with sutures. There is no evidence to suggest that the routine use of a pressure garment or compression dressing is beneficial. However, it appears that suture flap fixation does reduce seroma formation, simplify postoperative care and dressing, and thus allow early removal of drains and discharge. Drains are helpful for mechanical closure of dead space, but in breastconserving surgery this technique may preclude the use of a drain. However, previous studies have often been small in scale and poor in quality. Further studies should examine the effect of this technique on quality of life, cosmesis, and medical economics.

Key words

Seroma Flap fixation Prevention Breast cancer 



Breast-conserving surgery


Functional axillary lymphadenectomy


Randomized controlled trial


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Copyright information

© The Japanese Breast Cancer Society 2006

Authors and Affiliations

  • Katsumasa Kuroi
    • 1
    Email author
  • Kojiro Shimozuma
    • 2
  • Tetsuya Taguchi
    • 3
  • Hirohisa Imai
    • 4
  • Hiroyasu Yamashiro
    • 5
  • Shozo POhsumi
    • 6
  • Shinya Saito
    • 7
  1. 1.Department of SurgeryBreast Oncology Medical Corporation Nyuwakai Oikawa HospitalJapan
  2. 2.Department of Healthcare and Social ServicesUniversity of Marketing and Distribution SciencesJapan
  3. 3.Department of Surgical OncologyOsaka University Graduate School of MedicineJapan
  4. 4.Department of EpidemiologyNational Institute of Public HealthJapan
  5. 5.Department of Gastroenterological Surgery KyotoUniversity Graduate School of MedicineJapan
  6. 6.department of SurgeryNational Hospital Organization Shikoku Cancer CenterJapan
  7. 7.Department of Health ScienceKochi Women’s UniversityJapan

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