Skip to main content
Log in

Barriers to Pain Management

Focus on Opioid Therapy

  • Review Article
  • Published:
Clinical Drug Investigation Aims and scope Submit manuscript

Abstract

Despite the availability of effective pain treatments, there are numerous barriers to effective management resulting in a large proportion of patients not achieving optimal pain control. Chronic pain is inadequately treated because of a combination of cultural, societal, educational, political and religious constraints. The consequences of inadequately treated pain are physiological and psychological effects on the patient, as well as socioeconomic implications. Unreasonable failure to treat pain is viewed as unethical and an infringement of basic human rights. The numerous barriers to the clinical management of pain vary depending on whether they are viewed from the standpoint of the patient, the physician, or the institution. Identification and acknowledgement of the barriers involved are the first steps to overcoming them. Successful initiatives to overcome patient, physician and institutional barriers need to be multifaceted in their approach. Multidisciplinary initiatives to improve pain management include dissemination of community-based information, education and awareness programmes to attempt to change attitudes towards pain treatment. A better awareness and insight into the problems caused by unrelieved pain and greater knowledge about the efficacy and tolerability of available pain management options should enable physicians to seek out and adhere to treatment guidelines, and participate in interventional and educational programmes designed to improve pain management, and for institutions to implement the initiatives required. Although much work is underway to identify and resolve the issues in pain management, many patients still receive inadequate treatment. Continued effort is required to overcome the known barriers to effective pain management.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Nicholson B. Responsible prescribing of opioids for the management of chronic pain. Drugs 2003; 63(1): 17–32

    Article  PubMed  Google Scholar 

  2. Gianni W, Madaio RA, Di Cioccio L, et al. Prevalence of pain in elderly hospitalized patients. Arch Gerontol Geriatr 2010; 51(3): 273–6

    Article  PubMed  CAS  Google Scholar 

  3. Brennan F, Carr DB, Cousins M. Pain management: a fundamental human right. Anesth Analg 2007; 105(1): 205–21

    Article  PubMed  Google Scholar 

  4. Institute for Clinical Systems Improvement. Health care guideline: Assessment and management of acute pain. [Online] 2008; Available from: http://www.icsi.org/pain_acute/pain__acute__assessment_and_management_of__3.html

  5. Carr DB, Goudas LC. Acute pain. Lancet 1999; 353(9169): 2051–8

    Article  PubMed  CAS  Google Scholar 

  6. McCaffery M. The patient’s report of pain. Am J Nurs 2001; 101(12): 73–4

    Article  PubMed  CAS  Google Scholar 

  7. Kane RL, Bershadsky B, Rockwood T, et al. Visual Analog Scale pain reporting was standardized. J Clin Epidemiol 2005; 58(6): 618–23

    Article  PubMed  Google Scholar 

  8. Farrar JT, Young Jr JP, LaMoreaux L, et al. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain 2001; 94(2): 149–58

    Article  PubMed  CAS  Google Scholar 

  9. National Pain Foundation. New survey indicates majority of Americans in pain. [Online] 2008; Available from: http://www.nationalpainfoundation.org/pdfs_states/CompleteSurvey.pdf

  10. Martell BA, O’Connor PG, Kerns RD, et al. Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Ann Intern Med 2007; 146(2): 116–27

    Article  PubMed  Google Scholar 

  11. Manchikanti L, Vallejo R, Manchikanti KN, et al. Effectiveness of long-term opioid therapy for chronic noncancer pain. Pain Physician 2011; 14(2): E133–56

    PubMed  Google Scholar 

  12. Bennett MI, Flemming K, Closs SJ. Education in cancer pain management. Curr Opin Support Palliat Care 2011; 5(1): 20–4

    Article  PubMed  Google Scholar 

  13. Jacobsen R, Moldrup C, Christrup L, et al. Patient-related barriers to cancer pain management: a systematic exploratory review. Scand J Caring Sci 2009; 23(1): 190–208

    Article  PubMed  Google Scholar 

  14. National Cancer Institute. Pain PDQ(R). [Online] 2011; Available from: http://www.cancer.gov/cancertopics/pdq/supportivecare/pain/HealthProfessional

  15. Fairchild A. Under-treatment of cancer pain. Curr Opin Support Palliat Care 2010; 4(1): 11–5

    Article  PubMed  Google Scholar 

  16. Oldenmenger WH, Sillevis Smitt PA, van Dooren S, et al. A systematic review on barriers hindering adequate cancer pain management and interventions to reduce them: a critical appraisal. Eur J Cancer 2009; 45(8): 1370–80

    Article  PubMed  Google Scholar 

  17. Jacobsen R, Liubarskiene Z, Moldrup C, et al. Barriers to cancer pain management: a review of empirical research. Medicina (Kaunas) 2009; 45(6): 427–33

    Google Scholar 

  18. Resnik DB, Rehm M, Minard RB. The undertreatment of pain: scientific, clinical, cultural, and philosophical factors. Med Health Care Philos 2001; 4(3): 277–88

    Article  PubMed  CAS  Google Scholar 

  19. Glajchen M. Chronic pain: treatment barriers and strategies for clinical practice. J Am Board Fam Pract 2001; 14(3): 211–18

    PubMed  CAS  Google Scholar 

  20. Woolf A, Carr A, Frolich J, et al. Investigating the barriers to effective management of musculoskeletal pain: an international survey. Clin Rheumatol 2008; 27(12): 1535–42

    Article  PubMed  Google Scholar 

  21. Jacobsen R, Moldrup C, Christrup L, et al. Psychological and behavioural predictors of pain management outcomes in patients with cancer. Scand J Caring Sci 2010; 24(4): 781–90

    Article  PubMed  Google Scholar 

  22. Greer SM, Dalton JA, Carlson J, et al. Surgical patients’ fear of addiction to pain medication: the effect of an educational program for clinicians. Clin J Pain 2001; 17(2): 157–64

    Article  PubMed  CAS  Google Scholar 

  23. Broekmans S, Dobbels F, Milisen K, et al. Pharmacologic pain treatment in a multidisciplinary pain center: do patients adhere to the prescription of the physician? Clin J Pain 2010; 26(2): 81–6

    Article  PubMed  Google Scholar 

  24. Jarernsiripornkul N, Krska J, Richards RM, et al. Patient reporting of adverse drug reactions: useful information for pain management?. Eur J Pain 2003; 7(3): 219–24

    Article  PubMed  Google Scholar 

  25. Barry DT, Irwin KS, Jones ES, et al. Opioids, chronic pain, and addiction in primary care. J Pain 2010; 11(12): 1442–50

    Article  PubMed  Google Scholar 

  26. Alcenius M. Successfully meet pain assessment standards. Nurs Manage 2004; 35(3): 12

    Article  PubMed  Google Scholar 

  27. Anderson KO, Mendoza TR, Valero V, et al. Minority cancer patients and their providers: pain management attitudes and practice. Cancer 2000; 88(8): 1929–38

    Article  PubMed  CAS  Google Scholar 

  28. Paulson 3rd M, Dekker AH. Healthcare disparities in pain management. J Am Osteopath Assoc 2005; 105 (6 Suppl. 3): S14–17

    PubMed  Google Scholar 

  29. Peker L, Celebi N, Canbay O, et al. Doctors’ opinions, knowledge and attitudes towards cancer pain management in a university hospital. Agri 2008; 20(2): 20–30

    PubMed  Google Scholar 

  30. Breuer B, Fleishman SB, Cruciani RA, et al. Medical Oncologists’ Attitudes and Practice in Cancer Pain Management: A National Survey. J Clin Oncol 2011; 29(36): 4769–75

    Article  PubMed  Google Scholar 

  31. Gianni W, Madaio AR, Ceci M, et al. Transdermal buprenorphine for the treatment of chronic noncancer pain in the oldest old. J Pain Symptom Manage 2011; 41(4): 707–14

    Article  PubMed  CAS  Google Scholar 

  32. Ballantyne J, Klein J. Opioid therapy in addicted patients: background and perspective from the US. In: van Norman G, Jackson S, Rosenbaum S, Palmer S, editors. Clinical ethics in anesthesiology: a case-based textbook. New York: Cambridge University Press, 2011; 154–62

    Google Scholar 

  33. Eriksen J, Sjogren P, Bruera E, et al. Critical issues on opioids in chronic non-cancer pain: an epidemiological study. Pain 2006; 125(1–2): 172–9

    Article  PubMed  CAS  Google Scholar 

  34. Markman JD. Not so fast: the reformulation of fentanyl and breakthrough chronic non-cancer pain. Pain 2008; 136(3): 227–9

    Article  PubMed  CAS  Google Scholar 

  35. Kelly J, Cook S, Kaufman D, et al. Prevalence and characteristics of opioid use in the US adult population. Pain 2008; 138: 507–13

    Article  Google Scholar 

  36. World Health Organization. Ensuring balance in national policies on controlled substances: Guidance for availability and accessibility of controlled medicines 2011. Available from: http://www.who.int/medicines/areas/quality_safety/GLs_Ens_Balance_NOCP_Col_EN_sanend.pdf

  37. Chou R, Fanciullo GJ, Fine PG, et al. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain 2009; 10(2): 113–30

    Article  PubMed  CAS  Google Scholar 

  38. National Opioid Use Guideline Group. Canadian guideline for safe and effective use of opioids for CNCP. [Online] 2010; Available from: http://nationalpaincentre.mcmaster.ca/opioid/

  39. National Guideline Clearinghouse. Opioids in the management of chronic non-cancer pain: an update of American Society of the Interventional Pain Physicians’ (ASIPP) guidelines. [Online] 2011; Available from: http://www.guideline.gov/content.aspx?id=12521

  40. Breitbart W, Rosenfeld B, Passik SD. The Network Project: a multidisciplinary cancer education and training program in pain management, rehabilitation, and psychosocial issues. J Pain Symptom Manage 1998; 15(1): 18–26

    Article  PubMed  CAS  Google Scholar 

  41. Morlion B, Walch H, Yihune G, et al. The Pain Associates’ International Network Initiative: a novel practical approach to the challenge of chronic pain management in Europe. Pain Pract 2008; 8(6): 473–80

    Article  PubMed  Google Scholar 

  42. Sun VC, Borneman T, Ferrell B, et al. Overcoming barriers to cancer pain management: an institutional change model. J Pain Symptom Manage 2007; 34(4): 359–69

    Article  PubMed  CAS  Google Scholar 

  43. Stannard C, Johnson M. Chronic pain management-can we do better? An interview-based survey in primary care. Curr Med Res Opin 2003; 19(8): 703–6

    Article  PubMed  Google Scholar 

  44. Coluzzi F, Savoia G, Paoletti F, et al. Postoperative pain survey in Italy (POPSI): a snapshot of current national practices. Minerva Anestesiol 2009; 75(11): 622–31

    PubMed  CAS  Google Scholar 

  45. World Health Organization. WHO’s pain ladder. [Online] 2011; Available from: http://www.who.int/cancer/palliative/painladder/en/index.html

  46. Rajagopal MR, Joranson DE, Gilson AM. Medical use, misuse, and diversion of opioids in India. Lancet 2001; 358(9276): 139–43

    Article  PubMed  CAS  Google Scholar 

  47. Apolone G, Mangano S, Compagnoni A, et al. A multidisciplinary project to improve the quality of cancer pain management in Italy: background, methods, and preliminary results. J Ambul Care Manage 2006; 29(4): 332–41

    PubMed  Google Scholar 

  48. Craig KD, Versloot J, Goubert L, et al. Perceiving pain in others: automatic and controlled mechanisms. J Pain 2010; 11(2): 101–8

    Article  PubMed  Google Scholar 

  49. Collett BJ. Chronic opioid therapy for non-cancer pain. Br J Anaesth 2001; 87(1): 133–43

    Article  PubMed  CAS  Google Scholar 

  50. McNeill JA, Sherwood GD, Starck PL. The hidden error of mismanaged pain: a systems approach. J Pain Symptom Manage 2004; 28(1): 47–58

    Article  PubMed  Google Scholar 

  51. Brennan F, Cousins M. Pain relief as a human right. Pain Clinic Update 2004; 7(5): 1–4

    Google Scholar 

  52. Italian Parliament. Provisions to ensure access to palliative care and pain therapy [Italian]. [Online] 2010; Available from: http://www.parlamento.it/parlam/leggi/10038l.htm

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Stefano Maria Zuccaro.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zuccaro, S.M., Vellucci, R., Sarzi-Puttini, P. et al. Barriers to Pain Management. Clin Drug Investig 32 (Suppl 1), 11–19 (2012). https://doi.org/10.2165/11630040-000000000-00000

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/11630040-000000000-00000

Keywords

Navigation