Skip to main content
Log in

Drug Trials and Older People

Time to Embrace the Complexity of Age

  • Commentary
  • Published:
Drugs & Aging Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Fox C, Richardson, K, Maidment ID, et al. Anticholinergic medication use and cognitive impairment in the older population: the Medical Research Council Cognitive Function and Ageing study. J Am Geriatr Soc. Epub 2011 Jun 24

    Google Scholar 

  2. Guthrie B, McCowan C, Davey P, et al. High risk prescribing in primary care patients particularly vulnerable to adverse drug events: cross sectional population database analysis in Scottish general practice. BMJ 2011; 342: d3514

    Article  PubMed  Google Scholar 

  3. McMurdo ME, Witham MD, Gillespie ND. Including older people in clinical research. BMJ 2005; 331: 1036–7

    Article  PubMed  Google Scholar 

  4. Cherubini A, Oristrell J, Pla X, et al. The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. Arch Intern Med 2011; 171: 550–6

    Article  PubMed  Google Scholar 

  5. Crome P, Lally F, Cherubini A, et al. Exclusion of older people from clinical trials: professional views from nine European countries participating in the PREDICT study. Drugs Aging 2011; 28(8): 667–77

    Article  PubMed  Google Scholar 

  6. Beckett NS, Peters R, Fletcher AE, et al. Treatment ofhyper-tension in patients 80 years of age or older. N Engl J Med 2008; 358: 1887–98

    Article  PubMed  CAS  Google Scholar 

  7. Bartlam B, Lally F, Crome P, et al. The PREDICT study. Patients and carers views of older people’s participation in clinical trials. Eur Geriatr Med 2010; Suppl. 1S: S1

    Google Scholar 

  8. Habicht DW, Witham MD, McMurdo ME. The under-representation of older people in clinical trials: barriers and potential solutions. J Nutr Health Aging 2008; 12: 194–6

    Article  PubMed  CAS  Google Scholar 

  9. PREDICT charter [online]. Available from URL: http://www.predicteu.org/PREDICT_Charter/predict_charter.html [Accessed 2011 Jul 15]

Download references

Acknowledgements

M.D. Witham is funded by a Scottish Government CSO Clinician Scientist award. The author has no conflicts of interest that are directly relevant to the content of this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Miles D. Witham.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Witham, M.D. Drug Trials and Older People. Drugs Aging 28, 679–680 (2011). https://doi.org/10.2165/11595070-000000000-00000

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/11595070-000000000-00000

Keywords

Navigation