References
Kapoor A, Chuang W, Radhakrishnan N, et al. Cost effectiveness of venous thromboembolism pharmacological prophylaxis in total hip and knee replacement: a systematic review. Pharmacoeconomics 2010; 28 (7): 521–38
National Institute for Health and Clinical Excellence. Dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adults. Technology appraisal guidance 157. London: NICE, 2008 Sep
National Institute for Health and Clinical Excellence. Rivaroxaban for the prevention of venous thromboembolism after total hip or total knee replacement in adults. Technology appraisal guidance 170. London: NICE, 2009 Apr
Scottish Medicines Consortium. Drug advice: dabigatran etexilate, 75 mg and 110mg hard capsules (Pradaxa®). Glasgow: SMC, 2008 May
Scottish Medicines Consortium. Drug advice: rivaroxaban 10 mg film-coated tablets (Xarelto®). Glasgow: SMC, 2008 Nov
Wolowacz SE, Roskell NS, Maciver F, et al. Economic evaluation of dabigatran etexilate for the prevention of venous thromboembolism following total knee and hip replacement surgery. Clin Ther 2009; 31 (1): 194–212
Wolowacz SE, Roskell NS, Plumb JM, et al. Economic evaluation of dabigatran etexilate for the prevention of venous thromboembolism in patients aged over 75 years or with moderate renal impairment undergoing total knee or hip replacement. Thromb Haemost 2010; 103 (2): 360–71
Wolowacz SE, Hess N, Brennan VK, et al. Cost-effectiveness of venous thromboembolism prophylaxis in total hip and knee replacement surgery: the evolving application of health economic modelling over 20 years. Curr Med Res Opin 2008 Oct; 24 (10): 2993–3006
McCullagh L, Tilson L, Walsh C, et al. A cost-effectiveness analysis model comparing rivaroxaban and dabigatran etexilate with enoxaparin sodium as thromboprophylaxis after total hip and total knee replacement in the Irish healthcare setting. Pharmacoeconomics 2009; 27 (10): 829–46
Kakkar AK, Brenner B, Dahl OE, et al., RECORD2 Investigators. Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial. Lancet 2008; 372 (9632): 31–9
Lassen MR. Recent developments in the use of oral anticoagulants. Expert Opin Pharmacother 2009; 10 (11): 1769–81
Gómez-Outes A, Lecumberri R, Pozo C, et al. New anticoagulants: focus on venous thromboembolism. Curr Vasc Pharmacol 2009; 7 (3): 309–29
Merli G, Spyropoulos AC, Caprini JA. Use of emerging oral anticoagulants in clinical practice: translating results from clinical trials to orthopedic and general surgical patient populations. Ann Surg 2009; 250 (2): 219–28
Hull RD, Yusen RD, Bergqvist D. State-of-the-art review: assessing the safety profiles of new anticoagulants for major orthopedic surgery thromboprophylaxis. Clin Appl Thromb Hemost 2009; 15 (4): 377–88
Eriksson BI, Dahl OE, Rosencher N, et al., RE-NOVATE Study Group. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 2007; 370 (9591): 949–56
Eriksson BI, Borris LC, Friedman RJ, et al., RECORD1 Study Group. Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med 2008; 358 (26): 2765–75
Eriksson BI, Dahl OE, Rosencher N, et al. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial. J Thromb Haemost 2007; 5 (11): 2178–85
Lassen MR, Ageno W, Borris LC, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008; 358 (26): 2776–86
Acknowledgements
The authors are employees of Boehringer Ingelheim GmbH. Boehringer Ingelheim is the manufacturer of dabigatran etexilate (Pradaxa®).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Plumb, J.M., Clemens, A. & Monz, B.U. Cost Effectiveness of Venous Thromboembolism Pharmacological Prophylaxis in Total Hip and Knee Replacement: A Systematic Review. Pharmacoeconomics 28, 781–782 (2010). https://doi.org/10.2165/11535700-000000000-00000
Published:
Issue Date:
DOI: https://doi.org/10.2165/11535700-000000000-00000