Skip to main content
Log in

Onset of Lichen Planus During Treatment with Etanercept

  • Case Report
  • Published:
American Journal of Clinical Dermatology Aims and scope Submit manuscript

Abstract

The case is presented of a 24-year-old Caucasian man with moderate to severe psoriasis vulgaris resistant to traditional topical and systemic treatments who developed lichen planus (LP) during treatment with etanercept. Etanercept was effective, but LP developed after 8 months’ therapy. Although LP was deemed possibly related to etanercept therapy, the treatment was not discontinued and topical corticosteroids were applied with some clinical improvement. This is the second report of LP associated with etanercept treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Sobell JM, Kalb RE, Weinberg JM. Management of moderate to severe plaque psoriasis (part I): clinical update on antitumor necrosis factor agents. J Drugs Dermatol 2009; 8: 147–54

    PubMed  Google Scholar 

  2. Castelo-Soccio L, Van Voorhees AS. Long-term efficacy of biologics in dermatology. Dermatol Ther 2009; 22: 22–33

    Article  PubMed  Google Scholar 

  3. Jiménez-Puya R, Gómez-García F, Amorrich-Campos V, et al. Etanercept: efficacy and safety. J Eur Acad Dermatol Venereol 2009; 23: 402–5

    Article  PubMed  Google Scholar 

  4. Battistella M, Rivet J, Bachelez H, et al. Lichen planus associated with etanercept. Br J Dermatol 2008; 158: 188–90

    PubMed  CAS  Google Scholar 

  5. Garcovich S, Manco S, Zampetti A, et al. Onset of lichen planopilaris during treatment with etanerceptt. Br J Dermatol 2008; 158: 1161–3

    Article  PubMed  CAS  Google Scholar 

  6. Scheinfeld N. A comprehensive review and evaluation of the side effects of the tumor necrosis factor alpha blockers etanercept, infliximab and adalimumab. J Dermatolog Treat 2004; 15: 280–94

    Article  PubMed  CAS  Google Scholar 

  7. De Bandt M, Sibilia J, Le Loet X, et al. Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey. Arthritis Res Ther 2005; 7: 545–51

    Article  Google Scholar 

  8. Lee HH, Song IH, Friedrich M, et al. Cutaneous side-effects in patients with rheumatic diseases during application of tumour necrosis factor-alpha antagonists. Br J Dermatol 2007; 156: 486–91

    Article  PubMed  CAS  Google Scholar 

  9. Soliotis F, Glover M, Jawad AS. Severe skin reaction after leflunomide and etanercept in a patient with rheumatoid arthritis. Ann Rheum Dis 2002; 61: 850–1; comment in Ann Rheum Dis 2008; 67: 899-900

    Article  PubMed  CAS  Google Scholar 

  10. Vergara G, Silvestre JF, Betlloch I, et al. Cutaneous drug eruption to infliximab: report of 4 cases with an interface dermatitis pattern. Arch Dermatol 2002; 138: 1258–9

    Article  PubMed  Google Scholar 

  11. Richette P, Viguier M, Bachelez H, et al. Psoriasis induced by anti-tumour necrosis factor therapy: a class effect? J Rheumatol 2007; 34: 438–9

    PubMed  Google Scholar 

Download references

Acknowledgments

The authors would like to thank Mary Hines of inScience Communications who provided assistance with English-language editing. This assistance was funded by Pfizer. The authors report no conflicts of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Giuseppe Micali.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Musumeci, M.L., Lacarrubba, F. & Micali, G. Onset of Lichen Planus During Treatment with Etanercept. AM J Clin Dermatol 11 (Suppl 1), 55–56 (2010). https://doi.org/10.2165/1153428-S0-000000000-00000

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/1153428-S0-000000000-00000

Keywords

Navigation