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Etanercept Therapy for Psoriasis in a Patient with Numerous Comorbidities

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Abstract

A recent study demonstrated an association between psoriasis and dilated cardiomyopathy. Tumour necrosis factor alpha (TNFα) may be involved in the pathogenesis of dilated cardiomyopathy and therefore, anti-TNFα agents may play a role in the treatment of dilated cardiomyopathy. The case of a 51-year-old woman with severe psoriasis and numerous comorbidities including dilated cardiomyopathy is described. During treatment with etanercept, the patient’s psoriasis improved rapidly without any worsening of her other conditions. Etanercept was safe and effective in the treatment of severe psoriasis in a patient with numerous comorbidities, including dilated cardiomyopathy.

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Acknowledgments

The authors would like to thank Stephanie Blick of inScience Communications who provided assistance with English-language editing. This assistance was funded by Pfizer. The authors report no conflicts of interest.

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Authors and Affiliations

  1. Policlinico Universitario, Agostino Gemelli, Largo Agostino Gemelli 8, Rome, 00168, Italy

    Clara De Simone, Angelo Carbone & Giacomo Caldarola

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  1. Clara De Simone
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  2. Angelo Carbone
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  3. Giacomo Caldarola
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Correspondence to Clara De Simone.

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De Simone, C., Carbone, A. & Caldarola, G. Etanercept Therapy for Psoriasis in a Patient with Numerous Comorbidities. AM J Clin Dermatol 11 (Suppl 1), 49–50 (2010). https://doi.org/10.2165/1153425-S0-000000000-00000

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  • DOI: https://doi.org/10.2165/1153425-S0-000000000-00000

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