Childhood-onset psoriasis affects approximately one-third of the psoriatic population. Among many potential treatments of childhood psoriasis, biological agents are emerging as a valuable option in the management of this disease. InEurope, etanercept has recently been approved for children aged 8 years and over. Data froma well-designed clinical trial indicate that in children, etanercept effectively reduces psoriasis symptoms, with beneficial effects evident as early as 4 weeks after the initiation of treatment. Etanercept iswell tolerated; adverse effects are typically mild to moderate in severity. Early data from other biological agents are promising.
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Editorial assistance for the preparation of this manuscript was provided by Stephanie Blick of inScience Communications. This assistance was funded by Pfizer. The authors report no conflicts of interest.
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Bard, S., Torchia, D. & Schachner, L.A. Managing Pediatric Patients with Psoriasis. AM J Clin Dermatol 11, 15–17 (2010). https://doi.org/10.2165/1153415-S0-000000000-00000
- Juvenile Rheumatoid Arthritis
- Plaque Psoriasis