CNS Drugs

, Volume 23, Issue 10, pp 817–835

Potential Influences of Complementary Therapy on Motor and Non-Motor Complications in Parkinson’s Disease

Review Article

DOI: 10.2165/11310860-000000000-00000

Cite this article as:
Zesiewicz, T.A. & Evatt, M.L. CNS Drugs (2009) 23: 817. doi:10.2165/11310860-000000000-00000


Nearly two-thirds of patients with Parkinson’s disease (PD) use vitamins or nutritional supplements, and many more may use other complementary therapies, yet <50% of patients have discussed the use of these complementary therapies with a healthcare professional. Physicians should be aware of the complementary therapies their patients with PD are using, and the possible effects of these therapies on motor and non-motor symptoms.

Complementary therapies, such as altered diet, dietary supplements, vitamin therapy, herbal supplements, caffeine, nicotine, exercise, physical therapy, massage therapy, melatonin, bright-light therapy and acupuncture, may all influence the symptoms of PD and/or the effectiveness of dopaminergic therapy. Preliminary evidence suggests complementary therapy also may influence non-motor symptoms of PD, such as respiratory disorders, gastrointestinal disorders, mood disorders, sleep and orthostatic hypotension. Whenever possible, clinicians should ensure that complementary therapy is used appropriately in PD patients without reducing the benefits of dopaminergic therapy.

Supplementary material

40263_2012_23100817_MOESM1_ESM.pdf (103 kb)
Supplementary material, approximately 105 KB.

Copyright information

© Adis Data Information BV 2009

Authors and Affiliations

  1. 1.Parkinson Research Foundation, Department of NeurologyUniversity of South FloridaTampaUSA
  2. 2.Department of NeurologyEmory University School of MedicineAtlantaUSA
  3. 3.FAAN, University of South FloridaTampaUSA

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