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Transdermal Granisetron: A Guide to Its Use in Preventing Nausea and Vomiting Induced by Chemotherapy

CNS Drugs volume 26, pages 787–790 (2012)Cite this article

Abstract

Transdermal granisetron (Sancuso®) is effective in the prevention of nausea and vomiting in patients with cancer who are receiving moderately or highly emetogenic chemotherapy for 3–5 days. Transdermal granisetron is noninferior to oral granisetron in this indication, and is generally well tolerated in this indication. Thus, transdermal granisetron provides a convenient option for the prevention of chemotherapy-induced nausea and vomiting, with the potential to improve patient compliance.

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Acknowledgements and Disclosures

This article was updated from Drugs 2009; 69 (18): 2597-605,[2] and was reviewed by S. Van Belle, Department of Medical Oncology, University Hospital Ghent, Ghent, Belgium.

The preparation of these articles was not supported by any external funding. During the peer review process, the manufacturer of the agent under review will be offered an opportunity to comment on the articles. Changes resulting from comments received will be made by the authors on the basis of scientific and editorial merit.

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  1. Adis, 41 Centorian Drive, Mairangi Bay, North Shore, Private Bag 65901, 0754, Auckland, New Zealand

    Gillian M. Keating, Sean T. Duggan & Monique P. Curran

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  1. Gillian M. Keating
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  2. Sean T. Duggan
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  3. Monique P. Curran
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Correspondence to Gillian M. Keating.

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Keating, G.M., Duggan, S.T. & Curran, M.P. Transdermal Granisetron: A Guide to Its Use in Preventing Nausea and Vomiting Induced by Chemotherapy. CNS Drugs 26, 787–790 (2012). https://doi.org/10.2165/11209440-000000000-00000

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  • DOI: https://doi.org/10.2165/11209440-000000000-00000

Keywords

  • Irritable Bowel Syndrome
  • Granisetron
  • Aprepitant
  • Palonosetron
  • Tropisetron