Skip to main content
Log in

TimeView

For Comparative Gene Expression Analysis

Applied Bioinformatics

Abstract

TimeView is a MATLAB® program that compares multiple temporal datasets from microarray experiments under two or more conditions, for example, temporal variation of cellular response upon exposure to different drugs. The current paucity of programs designed to efficiently compare and visualise gene expression profiles in such datasets led us to design TimeView, which also enhances data visualisation by plotting the expression profiles of a large number of genes on a single screen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Iizaka M, Furukawa Y, Tsunoda T, et al. Expression profile analysis of colon cancer cells in response to sulindac or aspirin. Biochem Biophys Res Commun 2002; 292(2): 498–512

    Article  PubMed  CAS  Google Scholar 

  2. Johnson JE, Stromvik MV, Silverstein KA, et al. TableView: portable genomic data visualization. Bioinformatics 2003; 19(10): 1292–3

    Article  PubMed  CAS  Google Scholar 

  3. Butte AJ, Bao L, Reis BY, et al. Comparing the similarity of time-series gene expression using signal processing metrics. J Biomed Inform 2001; 34(6): 396–405

    Article  PubMed  CAS  Google Scholar 

  4. De Hoon MJ, Imoto S, Miyano S. Statistical analysis of a small set of time-ordered gene expression data using linear splines. Bioinformatics 2002; 18(11): 1477–85

    Article  PubMed  Google Scholar 

  5. Filkov V, Skiena S, Zhi J. Analysis techniques for microarray time-series data. J Comput Biol 2002; 9(2): 317–30

    Article  PubMed  CAS  Google Scholar 

  6. Johnson RA, Wichern DW. Applied multivariate statistical analysis. 4th ed. Upper Saddle River (NJ): Prentice Hall, 1998

    Google Scholar 

Download references

Acknowledgements

This work was supported in part by a grant from the National Institute of Health, USA (GM55850-05A1). The gifts from Merck Research Laboratories and Sankyo Co. for supporting the work of WSH are gratefully acknowledged. We would Like to thank MSI for computing resources.

The authors have no conflicts of interest that are directly relevant to the content of this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Wei-Shou Hu.

Additional information

Availability: TimeView is available free of charge to all users at http://hugroup.cems.umn.edu/Research/Genomics/Timeview/timeview.htm. To use TimeView, users will require access to the commercial software MATLAB® (version 6.5). A help document is available on the TimeView website.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gadgil, M., Mehra, S., Kapur, V. et al. TimeView. Appl-Bioinformatics 5, 41–44 (2006). https://doi.org/10.2165/00822942-200605010-00005

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00822942-200605010-00005

Keywords

Navigation