Abstract
Results from a landmark study have shown that the ACE inhibitor ramipril prevents major cardiovascular events in patients with a history of vascular disease or diabetes mellitus. The Heart Outcomes Prevention Evaluation (HOPE) trial showed that ramipril reduces the risk of cardiovascular mortality, stroke or myocardial infarction (MI) by 22% in this patient group. Results were presented at the 21st Congress of the European Society of Cardiology [ Barcelona, Spain; August-September 1999 ], where HOPE investigators said that the study represents one of the greatest discoveries in heart disease treatment worldwide.
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Innes, C. Ramipril gives high HOPE to patients with cardiovascular disease. Inpharma Wkly. 1206, 15–16 (1999). https://doi.org/10.2165/00128413-199912060-00032
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DOI: https://doi.org/10.2165/00128413-199912060-00032